21.78 How will each of the following changes affect the rate of an enzyme-catalyzed reaction whose optimum pH is 7.4? Decreasing the temperature from 37͒C to 5͒C Increasing the temperature from 37͒C to 90͒C Increasing the pH from 7.4 to 10 Increasing the pH from 5 to 7.4 Book: GENERAL ORGANIC AND BIOLOGICAL CHEMISTRY BY SMITH 4TH EDITION

Q: Hydroxychloroquine is a weak Bronsted base.

A: According to Arrhenius' concept, an acid gives H+ ions in its aqueous solution and a base gives OH-…

Q: What advantage does the enzyme gain by forming an imine?

A: Now when we consider a carbonyl compound which undergoes tautomerism to form enol under the…

Q: 1st proteinWhat is the sixth amino acid? What is the 11th amino acid?What is the name of the first…

A: Approach to solving the question: Detailed explanation:    Examples: Key references:

Q: 1. When an amino acid has a negative charge coming from the carboxylic acid or a positive charge…

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: 13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active site,…

A: We have find out the enzyme, it's active sites and substrate.

Q: None

A: Approach to solving the question: Detailed explanation: Examples: Key references: Health Science

Q: How will each of the following changes affect the rate of an enzyme-catalyzed reaction whose optimum…

A: Enzymes are biological catalysts that are proteinaceous in nature. Several factors affect the rate…

Q: 16. An experiment was conducted for an enzyme catalyzed reaction and data was gathered in a table.…

A: Note: Since you have posted a question with multiple sub-parts, we will provide the solution only to…

Q: Draw possible hydrogen bonds between the side chains physiological pH. 1. Asn and Ser 2. Thr, try 3.…

A:

Q: 8. The following proteins represent a wide range of molecular weights and isoelectric points. Mr is…

A:

Q: 29.Which amino acid is ideal for the transfer of protons within the catalytic site of enzymes due to…

A: Histidine is an amino acid that possesses a unique property in its side chain. At biological pH,…

Q: Answer question 16.46

A: Step-by-Step Approach to Solving the QuestionIdentify Optimum pH from Graph:Observe the graph to…

Q: Identify the amino acids in the following tripeptide: HN-CH-C-NH-CH-C-NH-CH–C-O CH2 CH,OH…

A: Find the peptide linkage i.e. CONH linkage. Break the bond between Carbon and Nitrogen atom and thus…

Q: 10.) If the optimum pH of a particular enzyme is 4.3, which of the following will likely result in…

A: Each enzyme work efficiently over a range of pH value.The optimum pH for an enzyme depends on its…

Q: 18. Which of the statements below correctly a) An enzyme decreases the value of AGrxn. (b) An enzyme…

A: Ans 18. Enzymes are biological catalysts that speed up chemical reactions by lowering the activation…

Q: o Consider the following simple reaction. [P] [S] k₁ S P where K'eq k₂ = Which of the listed effects…

A: So, an enzyme catalyzing this simple reaction would lead to a decrease in ΔG++ and an increase in…

Q: 6. The pka of formic acid is 3.750. What is the Ka of formic acid?

A: The answer to Question No. 6 is given as -

Q: At 25 °C the pKb for propanoate, C2H5COC", is 9.13. What is the pKa for its conjugate acid? a. 4.87…

A:

Q: Choose from A-F. Two of this amino acid can react with each other (anoxidation reaction) and form a…

A: Amino acids are essential biomolecules. It has been found around 20  different amino acids are there…

Q: A transition-state analog ____. Select one: a. resembles the transition-state structure of the…

A: Transition state analogues are defined as a chemical species which resembles the transition state of…

Q: 7. Select the amino acid that is achiral SH HO OH HO HN HN HN HN A B

A:

Q: Draw the structure of alanine in a solution at pH = 0 2. Draw the structure of alanine in a…

A: Amino acids are  compounds that contain amino and carboxylate functional groups, along with a side…

Q: Answer number 16.8

A: Lysine: Lysine is a polar amino acid with a basic side chain. Its R group contains an amino group,…

Q: nts 49 arning irtual Incorrect Question 73 How is the following amino acid classified? 0 H3N-CHC-0…

A: The given structure H3N-CHC-O CH2 C=O represents an amino acid. Amino acids are organic compounds…

Organic Chemistry of Metabolic Pathways

Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.

Glucogenesis

Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general  definition for glucogenesis or gluconeogenesis is as follows,