2. The following pyrrole derivative is a drug under development for schizophrenia and it is prepared by Knorr synthesis. Identify the structure of the two starting materials (ketone and a-aminoketone) required for the synthesis. CH3 H3C, N. CH3 Also, assign the absolute stereochemistry to the chiral centres contained in this drug.

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2. The following pyrrole derivative is a drug under development for schizophrenia and it is
prepared by Knorr synthesis. Identify the structure of the two starting materials (ketone
and a-aminoketone) required for the synthesis.
CH3
H
H3C,
CH3
H
Also, assign the absolute stereochemistry to the chiral centres contained in this drug.
Transcribed Image Text:2. The following pyrrole derivative is a drug under development for schizophrenia and it is prepared by Knorr synthesis. Identify the structure of the two starting materials (ketone and a-aminoketone) required for the synthesis. CH3 H H3C, CH3 H Also, assign the absolute stereochemistry to the chiral centres contained in this drug.
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