Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
Hi could you do question 2 please? Thank you
![Commercial Aspirin (acetylsalicylic acid or ASA) is an ester of
salicylic acid. It is one of the most commonly used drugs in the
world. First Nations peoples also used salicylic acid for
medicinal purposes-their sources however, such as willow
bark, were natural.
Today's commercial Aspirin uses modifications like
esterification to provide pain relief with fewer negative side
effects. The commercial Aspirin synthesis is accomplished using
benzene as a reactant. The reactions for the commercial
synthesis and for an alternative method are summarized in the
following diagrams:
crude
oil
Commercial Synthesis of Aspirin
benzene
OH
phenol
O
London
C-O-H
O-H
salicylic
acid
O-C-C-H
H
Aspirin](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb5fdd233-e947-4d5f-a3c0-4edca06f47b3%2F96c70935-4967-49f6-990e-36c8a2b91d18%2Fwjr6xff_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Commercial Aspirin (acetylsalicylic acid or ASA) is an ester of
salicylic acid. It is one of the most commonly used drugs in the
world. First Nations peoples also used salicylic acid for
medicinal purposes-their sources however, such as willow
bark, were natural.
Today's commercial Aspirin uses modifications like
esterification to provide pain relief with fewer negative side
effects. The commercial Aspirin synthesis is accomplished using
benzene as a reactant. The reactions for the commercial
synthesis and for an alternative method are summarized in the
following diagrams:
crude
oil
Commercial Synthesis of Aspirin
benzene
OH
phenol
O
London
C-O-H
O-H
salicylic
acid
O-C-C-H
H
Aspirin
![oil of
wintergreen
extracted from
plant leaves
Alternative Method for Synthesis of Aspirin
C-O-C-H
O-H
methyl
salicylate
C-O-H
O-H
salicylic
acid
O-C-C-H
III
ÖH
Aspirin
1. Describe what happens in a substitution reaction. Identify a
step in the processes shown in which a substitution reaction
occurs.
2. Provide the structural formula for the substance used to
convert salicylic acid into Aspirin.
3. From a greening perspective, give two advantages and one
disadvantage of using the alternative method for
synthesizing Aspirin.
1) A substitution reaction is when the functional group of one chemical
compound is substituted by another group. A subsitution is shown in
Step 2.-H is substituted with &-CH3 group.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb5fdd233-e947-4d5f-a3c0-4edca06f47b3%2F96c70935-4967-49f6-990e-36c8a2b91d18%2F0drp5ma4_processed.jpeg&w=3840&q=75)
Transcribed Image Text:oil of
wintergreen
extracted from
plant leaves
Alternative Method for Synthesis of Aspirin
C-O-C-H
O-H
methyl
salicylate
C-O-H
O-H
salicylic
acid
O-C-C-H
III
ÖH
Aspirin
1. Describe what happens in a substitution reaction. Identify a
step in the processes shown in which a substitution reaction
occurs.
2. Provide the structural formula for the substance used to
convert salicylic acid into Aspirin.
3. From a greening perspective, give two advantages and one
disadvantage of using the alternative method for
synthesizing Aspirin.
1) A substitution reaction is when the functional group of one chemical
compound is substituted by another group. A subsitution is shown in
Step 2.-H is substituted with &-CH3 group.
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