2. A research study was done to test whether aspirin was beneficial in reducing myocardial infarctions. The study population consisted of over 9,565 hospital workers who were randomly assigned to either aspirin or a placebo. A total of 6,146 did not have any attack and 5,138 of them took aspirin. Of the 4,042 who took a placebo, 3,034 had an attack. WITH MI ATTACK NO MI ATTACK ТОTAL ASPIRIN PLACEBO ТOTAL a. What is the incidence among those who were exposed? Use 1,000 as the multiplication factor and answer should be in whole numbers. b. What is the incidence among those who were not exposed? Use 1,000 as the multiplication factor
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- A pharmaceutical company proposed a vaccine that would combat paralytic polio. Two independent random samples were collected from the population. One random sample of 201,229 was given the placebo, and among them 100,910 contracted paralytic polio. The other random sample of 200,745 was given the vaccine, and among them 50,033 people ended up contracting paralytic polio. Let the true proportion of cases of paralytic polio given placebo be p1p1 and the true proportion of cases of paralytic polio given vaccine be p2. Calculate the upper bound of a 95% confidence interval for p1−p2. Round your answer to three decimal places.You are interested in testing if there is a difference in weight-loss between 3 popular diet types; low calorie, low fat and low carb. Participants are randomly assigned one of the three groups or a control group. The control group will be told that are participating in a weight-loss study, but will not be following any particular diet. This is to study the placebo effect, weight-loss from just participating in the study. At the start of the study, each participant's weight is recorded in pounds. After 8 weeks they are weighed again, and the weight difference is recorded. A positive value represents a weight loss while a negative value represents a weight gain. Test at 5% significance. Round answers to 3 decimal places. Diet Type Low Calorie Low Calorie Low Calorie Low Calorie Low Calorie Low Fat Low Fat Low Fat Low Fat Low Fat Low Carb Low Carb Low Carb Low Carb Low Carb Control Control Control Control Control Pounds Lost 6.9 4.7 3.5 7.7 5.9 3.8 1.4 3.8 5.2 2 4.9 2.6 2.7 5.6 3.4 1.3…A paper describes a study of the use of MRI (Magnetic Resonance Imaging) exams in the diagnosis of breast cancer. The purpose of the study was to determine if MRI exams do a better job than mammograms of determining if women who have recently been diagnosed with cancer in one breast have cancer in the other breast. The study participants were 950 women who had been diagnosed with cancer in one breast and for whom a mammogram did not detect cancer in the other breast. These women had an MRI exam of the other breast, and 101 of those exams indicated possible cancer. After undergoing biopsies, it was determined that 30 of the 101 did in fact have cancer in the other breast, whereas 71 did not. The women were all followed for one year, and four of the women for whom the MRI exam did not indicate cancer in the other breast were subsequently diagnosed with cancer that the MRI did not detect. The accompanying table summarizes this information. Cancer Cancer Not Present Present Total MRI…
- A researcher is conducting an experimental study on the effect of aspirin on heart attack risk. In order to assign who will receive aspirin and who will receive a placebo, she first divides her study into three age groups (18-29, 30-49, and 50 or older). She then randomly assigns individuals within these age groups to either receive aspirin or the placebo. This is an example of a cluster ?A study was conducted to determine whether big-city and small-town dwellers differed in their helpfulness to strangers. In this study, the investigators rang the doorbells of strangers living in a large City or small towns in the vicinity. They explained they had misplaced the address of a friend living in the neighbourhood and asked to use the phone. The following data show the number of individuals who admitted or did not admit the strangers (the investigators) into their homes: Helpfulness to strangers Admitted strangers into their home Didnot admit strangers into their home Big city dwellers 60 90 Small town dwellers 70 30 State the dependent and independent variable Is this a directional or non directionalResearchers are interested in determining if there is a difference in the proportion of women who choose the different types of treatments for those diagnosed with Ductal Carcinoma in Situ (DIS) breast cancer, which is a form of breast cancer that occurs in the Breast Ducts and has not spread. Following a diagnoses of DCIS, women can choose between three different treatment plans: a mastectomy or a lumpectomy followed by radiation therapy or a lumpectomy followed by Adjuvant Endocrine therapy. A random sample of 500 women diagnosed with DCIS breast cancer was obtained. Of the 500 women, 190 chose to have a mastectomy, 150 chose to have a lumpectomy followed by radiation, and 160 chose to have a lumpectomy followed by Adjuvant Endocrine therapy. At the 1% significance level, what conclusion can be reached?
- In a randomized clinical trial, 888 people were placed given Drug A and 930 were given Drug B. The researcher's goals were to determine which drug had better efficacy against T.B. Of those who were given Drug A, 300 contracted T.B. Of the subjects who were given Drug B, 500 contracted T.B. Calculate and interpret the risk ratio of Drug B compared to Drug A for getting T.B.? 10. In Box City, an influenza vaccine was tested on 1,000 people, 400 males and 600 females. Of the males, 50% contracted influenza after vaccination versus 30% of the females. Calculate and interpret the risk ratio of females compared to males of contracting influenza. 11.A group of 600 patients who suffer from seasonal allergies is asked to participate in a study to determine the effectiveness of a new medication. The patients are divided randomly into two groups, one was given the actual medication and one received a placebo pill. After 2 months of treatment, 64% of the patients who took the medication had fewer allergy symptoms, while only 36% of those who took the placebo had fewer allergy symptoms. a. What is the treatment variable? b. What is the response (or outcome) variable? c. Was this an observational study or a controlled experiment? Explain how you know. d. Assuming the rest of the study was well-designed, use your answers to discuss whether it would be reasonable to conclude that taking the new medication caused fewer allergy symptoms.You are concerned that nausea may be a side effect of Tamiflu, but you cannot just give Tamiflu to patients with the flu and say that nausea is a side effect if people become nauseous. This is because nausea is common for people who have the flu.Past studies state that about 33% of people who get the flu experience nausea. You collected data on 2248 patients who were taking Tamiflu to relieve symtoms of the flu, and found that 810 experienced nausea. You decide to carry out a simulation to test the claim that the percentage of people who take Tamiflu for the relief of flu symtoms and experience nausea is greater than 33%.a) Identify the null and alternative hypotheses.H0H0: ? p = p ≠ p < p > p ≤ p ≥ μ = μ ≠ μ < μ > μ ≤ μ ≥ H1H1: ? p = p ≠ p < p > p ≤ p ≥ μ = μ ≠ μ < μ > μ ≤ μ ≥
- You are interested in testing if there is a difference in weight-loss between 3 popular diet types; low calorie, low fat and low carb. Participants are randomly assigned one of the three groups or a control group. The control group will be told that are participating in a weight-loss study, but will not be following any particular diet. This is to study the placebo effect, weight-loss from just participating in the study. At the start of the study, each participant's weight is recorded in pounds. After 8 weeks they are weighed again, and the weight difference is recorded. A positive value represents a weight loss while a negative value represents a weight gain. Test at 10% significance. Round answers to 3 decimal places. Diet Type Low Calorie Low Calorie Low Calorie Low Calorie Low Calorie Low Fat Low Fat Low Fat Low Fat Low Fat Low Carb Low Carb Low Carb Low Carb Low Carb Control Control Control Control Control Pounds Lost 5.3 6.6 10.5 6.4 8.9 5 4 0.2 2.9 2.6 4.6 2.9 0.8 2.4 2.5 1.9…A case-control study was conducted to find out whether meditation practice was negatively associated with blood pressure among adults. Investigators identified 100 adults with high blood pressure. The investigators recruited 400 people without normal or low blood pressure into the control group. All participants were given a questionnaire asking them whether they practiced meditation during the previous year. Among participants with high blood pressure, 25 reported that they practiced meditation during the previous year; a total of 125 control participants reported meditation. a. Create a 2x2 table for exposition (meditation) and health problem (high blood pressure). b. Calculate the odds ratio of having high blood pressure relative to those who meditated during the last year relative to those who did not. c. Interpret this odds ratio.