2-Bromopalmitoyl-CoA inhibits the oxidation of palmitoyl-CoAby isolated mitochondria but has no effect on the oxidation ofpalmitoylcarnitine. What is the most likely site of inhibition by2-bromopalmitoyl-CoA?

Carnitine shuttle is a way by which long-chain fatty acyl-CoA is transported inside mitochondria for…

Answered: 2-Bromopalmitoyl-CoA inhibits the…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter23: Fatty Acid Catabolism

Section: Chapter Questions

Problem 16P: Extending the Mechanism of Methylmalonyl-CoA Mutase to Similar Reactions Based on the mechanism for...

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2-Bromopalmitoyl-CoA inhibits the oxidation of palmitoyl-CoA by isolatedmitochondria but has no effect on the oxidation of palmitoylcarnitine. What is the most likely site of inhibition by 2-bromopalmitoyl-CoA?
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2-Bromopalmitoyl-CoA inhibits the oxidation of palmitoyl-CoA by isolated mitochondria but has no effect on the oxidation of palmitoylcarnitine. What is the most likely site of inhibition by 2-bromopalmitoyl-CoA?