2 11 E III IV 6 HOOL od 1. The pedigree above shows the passing on of colorblindness. What sex is MOST likely to be carriers of colorblindne 2. Why does individual IV-7 (a female) have colorblindness? 3. Why do all the daughters in generation II carry the colorblind gene? 4. List 2 IV generation colorblind males. 10
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- The following pedigree shows the pattern of inheritance of red green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in red. What is the chance that a son of the third-generation female indicated by the arrow will be color-blind if the father is a normal man? If the father is color-blind?14. ii) If Individuals #6 and #7 have another daughter what are the chances that she will be affected. 1 II IV a) The pedigree above shows the passing on of colorblindness. What sex is MOST likely to be carriers of colorblindness? b) Why does individual IV-7 (a female) have colorblindness? c) Why do all the daughters in generation II carry the colorblind gene? d) List two h generation colorblind males. 15. Explain sex linked inheritance with examples. 16. Explain what happens during these following sicknesses and why it happens? i) Sickle cell anemia i Hemophilia 17. What do you understand by the term "Multiple Alleles"? Define the followings: Trait true breeding cross P generation F1 generation monohybrid cross F2 generation dominant recessive law of segregation genotype phenotype homozygous heterozygous test cross dihybrid cross law of independent assortment pedigree autosomal recessive Punnett square autosomal inheritance autosomal dominant2. Can a color-blind female have a son that has normal vision? Color blindness is caused by a sex-linked recessive allele. Explain. Do the Punnett square. *use N = normal vision and n = color blind over X and Y chromosomes. 3. Muscular dystrophy is a sex-linked trait. What parental genotypes could produce a female with=muscular dystrophy? Do the Punnett square. *use M = normal muscles, and m = muscles missing dystrophin protein over X and Y chromosomes. 4. In humans, red-green color-blindness is due to a recessive gene X^c. Normal vision results from the dominant gene X^c. If a homozygous woman of normal vision marries a color-blind man, what type of vision will be expected in their children?
- 5. A woman who is a carrier for colorblindness marries a colorblind man. The woman nas 5 nngers on each hand and the man, whose father had father had 5 fingers, has 6 fingers. (Polydactyly-have 6 fingers on each hand-is inherited as an autosomal dominant trait. What percent of their children do you expect to be colorblind with 5 fingers? man with type AB blood is married to a woman with type O blood. They have 2 natural children 01one adopted child. 'One child has type A blood, one has type B blood and the other has type O blood. Whi s adopted?7. Hereditary ichthyosis in humans is a sex-linked trait. If a normal male and a carrier female produce offspring, what will be the phenotypic ratios of: Normal females to scaly females? Normal males to scaly males? 8. Raedwald is color blind. His four sisters and his parents all have normal color vision. Who passed this condition on to Raedwald, and what can be said for certain about the genotypes of his maternal and paternal grandparents? wwwwM2. The following is a pedigree of a family in which a rare form of X-linked colorblindness is found (filled-in symbols). II 2 II 3 4 a. Label the genotypes of as many family members as the available information permits. Remember that this gene is located on the X-chromosome when writing out genotypes. b. Is the colorblindness trait recessive or dominant? Explain how you know.
- 4:12 8. A heterozygous round seeded plant (Rr) is crossed with a homozygous round seeded plant (RR). Give the expected probabilities for each genotype and phenotype. 9. A homozygous round seeded plant is crossed with a homozygous wrinkled seeded plant. What are the genotypes of the parents? X 10. In pea plants purple flowers are dominant white flowers. If two white flowered plants are crossed, what percentage of their offspring will be white flowered? % Previous What percentage of the offspring will also be homozygous? ZOOM + 12. Two plants, both heterozygous for the gene that controls flower color are crossed. Give the expected RATIOS for each genotype and phenotype. Phenotype Ratio - Gentoype Ratio - 11. A white flowered plant is crossed with a plant that is heterozygous for the trait. What percentage of the offspring will have purple flowers? 13. In guinea pigs, the allele for short hair is dominant over long hair. Two short haired guinea pigs are mated several times. Out of 100…6. The pedigree below traces the inheritance of a particular disorder. Circles are females, squares are males. Shaded symbols are affected with the disorder (NOTE: "half-shaded" symbols are NOT used here, for heterozygous individuals). What is the mode of inheritance of this disorder: is it dominant or recessive? Autosomal or X-linked? What is the genotype of the three numbered individuals? 1 2. 3.Incomplete Dominance 1. In snapdragons, red flower color (R) is incompletely dominant over white flower color (r). The hybrids or heterozygous plants (Rr) are pink in color. a) Show the genotype for a white flower and for a red flower. b) If a red-flowered plant is crossed with a white-flowered plant, what are the genotypes and phenotypes of the F1 generation plants? Show your work. c) What genotypes and phenotypes will be produced in the F2 generation? Show your work? the the o doa A t r th s beirs ard the phenorypic and wo ran aials pring fro d) How did the genotypic and phenotypic ratio compare to each other in this incomplete dominance cross? gonarypi and e) What would the phenotypic ratio have been if this had been complete dominance?
- 1. Red-green colorblindness is caused by a recessive allele (x) at an X-linked gene, and albinism is caused by a recessive allele (a) at an autosomal gene. A phenotypically normal woman (Sara) has a father who is colorblind, and she knows that she is a carrier for albinism. She plans to have a child with a colorblind man (Abdul) who is also a carrier for albinism. What is the probability that Sara and Abdul's child will have one of the conditions, but not both? (C. Follow the steps below to answer this question. a) What is the cross? b) What are the target genotypes? Note: it might be useful to come back to this one and double- check it after you have completed step c, below. Break this down to the single gene level by answering the following questions: a. What is the proportion of normal to albino offspring? Show the Punnett square: b. What is the proportion of normal to colorblind offspring? Show the Punnett square: d) What is the probability that Sara and Abdul's child will have one…5A. In shorthorn cattle, the polled condition is dominant over horned. Also, the heterozygous condition (RW) of red coat (R) and white coat (W) is roan, an example of codominance. (The roan coat contains both red and white fur because neither allele is dominant over the other). If a homozygous polled, white male is bred to a horned, red female, what will be the appearance of the F1 generation? Horned: r: Roan Coat: a. Possible genotypes for Polled condition Coat:_ ossible geno c. Male genotype: d. Female genotype: Male possible gametes Female possible gametes e. f. Genotypic Ratio: g. Phenotypic Ratio 5B, Breed two of the F1 generation to determine the possibilities in the F2 generation. Horned: a. Possible genotypes for Polled condition b. Possible genotypes for Red coat: White Coat:_ Roan Coat: c. Male genotype: d. Female genotype Male possible gametes Female possible gametes: f. Genotypic Ratio: g. Phenotypic Ratio5A. In shorthorn cattle, the polled condition is dominant over horned. Also, the heterozygous condition (RW) of red coat (R) and white coat (W) is roan, an example of codominance. (The roan coat contains both red and white fur because neither allele is dominant over the other). If a homozygous polled, white male is bred to a horned, red female, what will be the appearance of the F1 generation? a. Possible genotypes for Polled condition: Horned: b. Possible genotypes for Red coat:White Coat: Roan Coat: c. Male genotype Male possible gametes: Female genotypeFemale possible gametes: e. f. Genotypic Ratio: g. Phenotypic Ratio: