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19. Which of the following is true? A. Water molecules that surround a less polar molecule in solution are immobile and ordered. B. Salt bridges are often found on the surface of proteins where they are stabilized by water. C. Micelles are stabilized in water by interactions of nonpolar molecules with each other. D. Hydrophobic interactions are sometimes called "bonds", because each one is as strong as a covalent bond. E. Both A and C 20. Which of the following is true? A. Since the pKa of acetic acid is 4.8, it can be used to prepare a buffer to maintain physiological pH. B. The buffering capacity of a weak acid and its conjugate base is strongest when the pH = pka. C. Synthetic compounds used as buffers are not as valuable for experiments as naturally occurring compounds used as buffers. D. All of the above E. None of the above

19. Which of the following is true? A. Water molecules that surround a less polar molecule in solution are immobile and ordered. B. Salt bridges are often found on the surface of proteins where they are stabilized by water. C. Micelles are stabilized in water by interactions of nonpolar molecules with each other. D. Hydrophobic interactions are sometimes called "bonds", because each one is as strong as a covalent bond. E. Both A and C 20. Which of the following is true? A. Since the pKa of acetic acid is 4.8, it can be used to prepare a buffer to maintain physiological pH. B. The buffering capacity of a weak acid and its conjugate base is strongest when the pH = pka. C. Synthetic compounds used as buffers are not as valuable for experiments as naturally occurring compounds used as buffers. D. All of the above E. None of the above

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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### Multiple Choice Questions on Molecular Interactions and Buffer Chemistry #### Question 19: Which of the following is true? A. Water molecules that surround a less polar molecule in solution are immobile and ordered. B. Salt bridges are often found on the surface of proteins where they are stabilized by water. C. Micelles are stabilized in water by interactions of nonpolar molecules with each other. D. Hydrophobic interactions are sometimes called “bonds” because each one is as strong as a covalent bond. E. Both A and C **Explanation:** - **A** is correct as less polar molecules cause water to organize in a more structured, less mobile fashion. - **B** is correct in the context of solubilizing protein surfaces with ionic interactions. - **C** is true as micelles are formed by nonpolar groups clustering to avoid water. - **D** Hydrophobic interactions are not as strong as covalent bonds and are not accurately termed as 'bonds'. #### Question 20: Which of the following is true? A. Since the pKa of acetic acid is 4.8, it can be used to prepare a buffer to maintain physiological pH. B. The buffering capacity of a weak acid and its conjugate base is strongest when the pH = pKa. C. Synthetic compounds used as buffers are not as valuable for experiments as naturally occurring compounds used as buffers. D. All of the above E. None of the above **Explanation:** - **A** is partially true; however, the physiological pH is typically around 7.4. - **B** is correct; the buffering capacity is indeed best when pH equals the pKa of the buffer. - **C** is subjective; the value of synthetic vs. naturally occurring buffers depends on the application.
Transcribed Image Text:### Multiple Choice Questions on Molecular Interactions and Buffer Chemistry #### Question 19: Which of the following is true? A. Water molecules that surround a less polar molecule in solution are immobile and ordered. B. Salt bridges are often found on the surface of proteins where they are stabilized by water. C. Micelles are stabilized in water by interactions of nonpolar molecules with each other. D. Hydrophobic interactions are sometimes called “bonds” because each one is as strong as a covalent bond. E. Both A and C **Explanation:** - **A** is correct as less polar molecules cause water to organize in a more structured, less mobile fashion. - **B** is correct in the context of solubilizing protein surfaces with ionic interactions. - **C** is true as micelles are formed by nonpolar groups clustering to avoid water. - **D** Hydrophobic interactions are not as strong as covalent bonds and are not accurately termed as 'bonds'. #### Question 20: Which of the following is true? A. Since the pKa of acetic acid is 4.8, it can be used to prepare a buffer to maintain physiological pH. B. The buffering capacity of a weak acid and its conjugate base is strongest when the pH = pKa. C. Synthetic compounds used as buffers are not as valuable for experiments as naturally occurring compounds used as buffers. D. All of the above E. None of the above **Explanation:** - **A** is partially true; however, the physiological pH is typically around 7.4. - **B** is correct; the buffering capacity is indeed best when pH equals the pKa of the buffer. - **C** is subjective; the value of synthetic vs. naturally occurring buffers depends on the application.
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