Aspartate has 3 pka'sdesiaci ovi bas quoi lyx000-posto quos17.15 The structure of aspartic acid (pl = 2.8) is shownbelow. Draw the structure of aspartic acid at pH= 1, 2.8, 7and 10.O=SlH₂N-CH-C-OHibong od pK₂2 = 9.6CH₂c=28 mil010pka1 = 1.88251110001q1637nado não quer 2508:30)time-bris pK₂3 = 3.65 OH to 2201 Tobingsq

The objective of this question is to show the aspartic acid, with a pKa of , undergoes protonation…

17.15 The structure of aspartic acid (pl = 2.8) is shown below. Draw the structure of aspartic acid at pH= 1, 2.8, 7 and 10. O rod opg H₂N-CH-C-OH pK₂2 = 9.6 91 CH₂ C1O SW as not bed-pka1 = 1.88 bspK₂3 = 3.65 OH pka3 sbitqoq e

17.15 The structure of aspartic acid (pl = 2.8) is shown below. Draw the structure of aspartic acid at pH= 1, 2.8, 7 and 10. O rod opg H₂N-CH-C-OH pK₂2 = 9.6 91 CH₂ C1O SW as not bed-pka1 = 1.88 bspK₂3 = 3.65 OH pka3 sbitqoq e

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: HO pk₂4.01 NH₂ 11 pka 10.01 OH pk 2.19 O O Glutamic acid derivative d) Draw the most abundant ion of…

A: Glutamic aic derivativepH of derivative = 7.0

Q: calculate the % yield of preparation of 2-aminobenzoic acid: mass of phthaliamide = 2.95g mass of…

A: In the question two mass of 2-aminobenzoic acid is given. Hence, the individual percent yield is…

Q: The given dipeptide is Asp‑Tyr. Indicate the charge state for each structure at the given pH by…

A: The pH 1 is highly acidic. Hence the peptide will exist as an ammonium carboxylic acid. The terminal…

Q: Glutamic acid is a naturally occuring a-amino acid that contains a carboxy group in its R group side…

A: a. At pH=1, there is a highly acidic medium, the amino group gains a proton and the positive form of…

Q: At very low pH, alanine is a diprotic acid that can be represented as H3N1-CH(CH3)-COOH. The pKa of…

A: A diprotic acid contains two types of acidic groups. The amino acid contains these two groups: 1.…

Q: All amino acids have two ionizable functional groups: an α‑amino group (average p?a of 9.4) and an…

A: The ionization of Aspartic acid according to the question is shown in the figure:

Q: Which functional group on furosemide's structure below is most likely to be negatively charged at…

A: Here we have to say which functional group is most likely to be negatively charged at physiological…

Q: Consider a tetrapeptide, Gly-Gly-Lys-Ala. pka1 of Gly = 2.35 pka2 of Gly = 9.78 pka1 of Ala = 2.35…

A: The isoelectric point (pI): It is the pH at which a particular molecule carries no net electrical…

Q: The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COO™…

A: The objective of this question is to find the pH of histidine.

Q: what are the lewis structures of these: H3PO4 SO42- Palmitic acid (in pH 7.4) Glycerol Water…

A: Lewis structure are drawn by making dots on the symbol of atom the number of dots are equal to their…

Q: 13- If you were to have a mythical AA based on Aspartic acid in which the carboxylate on the side…

A: Amino acids are the molecules that contain amino and carboxylic acid group. When both these groups…

Q: a) Canavanine is an amino acid that is produced by some legume plants. It is not used in proteins…

A: Canavanine has a similar structure of Arginine. Hence Canavanine has 3 groups that can be…

Q: Which of the structures below corresponds to the dipeptide cysteylananine? The parentamino acids are…

A: Amino acids contain carboxylic acid and an amine functional group on the same carbon atom. Amino…

Q: P What is the dominant form of aspartic acid (a triprotic acid) at a pH of 1.50 (pKa1 = 1.990, pKa2…

Q: Below is the structure of eicosapentaenoic acid (EPA) which is an omega-3 fatty acid. What would be…

A: IUPAC nomenclature is used for naming the organic compound as per recommended by international union…

Q: Methylamine, CH3-NH₂, is a weak base (pk = 3.36). Which of the following acids is sufficiently…

A: Given that, Methylamine(CH3NH2) is a weak base pKb=3.36 pKa+pKb=14 (at25C) pKa value for some acids…

Q: Which functional group on furosemide’s structure below is most likely to be negatively charged at…

Q: Lecithins are a type of glycerophospholipid. They are also called phosphatidylcholines and are…

A: the given lecithine molecule

Q: What is the ratio of base [A] to acid [HA] at pH 4, 5, 6 and 7 for an acid with a pK₂ of 6?

A: Buffer solution: The solution that resists the change in pH is known as a buffer solution. The…

Q: The amino acid His is triprotic with pK1 (α-COOH) = 1.82, pK2 (α-NH3+) = 9.17, and pK3 (side chain)…

A: If the pKa of acid is equal or lower than the pH of the solution then the acid will get deprotonated…

Q: 8. The following proteins represent a wide range of molecular weights and isoelectric points. Mr is…

Q: Balanced Chemical Equation Reaction Type: At completion of reactions: Grams of potassium chlorate…

Q: Phenolphthalein has a pKa of 9.7. It is colorless in its acid form and pink in its basic form. For…

Q: Identify the following amino acid in aqueous form (at pH = 7.0): (COO)–CH(NH3)–CH(OH)–CH3 A.…

A: Acidic and basic amino acid did not have equal number of acid and amine groups . For neutral amino…

Q: Methylamine, CH3-NH₂, is a weak base (pk = 3.36). Which of the following acids is sufficiently…

A: GIVEN DATA Methylamine, CH3-NH, , is a weak base (pkb, = 3.36). dissociation 50% at 25 C

Q: Which dipeptide(s), (i)-(iv), may be formed in the reaction of glycine and phenylalanine? Glycine…

A: Dipeptide is combination of two amino acid with the loss of water molecule. if glycine combine with…

Q: Consider an amino acid with the following pKa values: pKa1 = 2.71 and pK, = 9.31 At what pH value in…

A: Amino acids are amphoteric in nature due to the presence their ionizable α-amino and α-carboxylic…

Q: Question 6 of 25 > Modify lysine to show the predominant form at pH 7. Modify the amino acid by…

A: Amino acids are bullding blocks of proteins. pH measures how acidic or basic a solution is.

Q: Given that C6H11COOH has a pKa = 4.8 and C6H11N + H3 has a pKa = 10.7, what pH would you make the…

A: The compounds need to be charged to be dissolved in water. C6H11COOH is charged in its basic form.…

Q: If the pl for asparagine is 5.43, draw the structure at a pH of 9.5?

A: The pl for asparagine = 5.43 pH = 9.5

Q: For aspartic acid, the pka's of the a-COOH and a-NH3* are 2.1 and 9.8, respectively, whereas the pKa…

A: When pH is greater than pKa then depronated form. When pH is less than pKa then protonated form.…

Q: Aspartic acid has the following pKa values: Alpha carboxyl group =2.1 , side chain carboxylgroup =…

A: The question is based on the concept of amino acids. We need to draw the structure of aspartic acid…

Q: Calculate the pH at which the carboxyl R group of aspartic acid is 30% dissociated

A: Handerson Hasselbalch equation – Buffer solution is mixture of weak acid and its conjugate base.…

Q: Calculate the pH at which the carboxyl R group of aspartic acid is 30% dissociated

A: Handerson Hasselbalch equation – Buffer solution is mixture of weak acid and its conjugate base.…

Q: Provide the amino acid sequence for human inculin

A: Human insulin is one of the important human hormone that is produced by beta cells of pancreatic…

Q: 2+ The amino acid "arginine (Arg)" has the following form: Arg, HArg, H₂ Arg+, H3 Arg²+. Which is…

A: pH < pka (protonation) pH > pka (deprotonation) pH = 1/2 protonaton or deprotonation

Q: If an acid with a pKa of 5.0 is in an aqueous solution of pH = 5.5, what percentage of the acid is…

A: If the pH is greater than pKa then deprotonation occurs and it exists in deprotonation form. While…

Q: Consider acetic acid. What is the net charge on the molecule in a solution of acetic acid at pH of…

A: Acetic acid (CH3COOH) is a weak acid that can partially dissociate in water to form acetate ions…

Q: Draw the structure of alanine in a solution at pH = 0 2. Draw the structure of alanine in a…

A: Amino acids are compounds that contain amino and carboxylate functional groups, along with a side…

Q: Overall Charge

Q: Complete the table for the ionizable groups of the fictitious amino acid hypothetinine. pKa (to TWO…

A: The correct answer is given

Q: . Identify carbon atoms, by number, that are incorporated from this structure into the compounds…

A: The given compound is S-adenosyl methionine. For transmethylation reactions, this compound acts as a…

Q: The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COOH…

A: Molarity of Histidine solution = 0.11 MThe volume of Histidine solution taken = 80 mLpH of Histidine…

Concept explainers

Spectroanalytical Methods

Spectroanalytical methods measure the wavelength and intensity of radiations that are either emitted or absorbed by a molecular or atomic species. These methods are useful for evaluating the electronic or atomic arrangement of the molecules of a given analyte.

Question

Aspartate has 3 pka's
desiaci ovi bas quoi lyx000-posto quos
17.15 The structure of aspartic acid (pl = 2.8) is shown
below. Draw the structure of aspartic acid at pH= 1, 2.8, 7
and 10.
O=
Sl
H₂N-CH-C-OH
ibong od pK₂2 = 9.6
CH₂
c=
28 mil010
pka1 = 1.88
251110001q
1637
nado não quer 25
08:30)
time-bris pK₂3 = 3.65 OH to 2201 Tobingsq

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Introduction

Step 2: pH 1 value

Step 3: pH 2.8 value

Step 4: pH 7 value

Solution

Step by step

Solved in 5 steps with 6 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

The amino acid Asp is triprotic with pK₁ = 1.88, pK₂ = 9.60, and pK3 = 3.65. What is the charge of the a-NH3* functional group at pH 11? -1 What is the net charge of Asp at pH 11? [Select] = The amino acid Asp is triprotic with pK1: 1.88, pK2 = 9.60, and pK3 = 3.65.
Consider the hexapeptide S-H-I-R-M-P Draw the structure at pH 1.0. What is the charge at this point? Draw the structure at pH 7.4. What is the charge at this point? Determine the pl and draw its structure.
The amino acid histidine has ionizable groups with pK, values of 1.8, 6.0, and 9.2, as shown. COOH H₂N-CH CH, H pH = 1.29 COO H₂N-CH 1.8 CH pk, lonizable -COOH-COO- group Incorrect CH, H COO H₂N-CH 6.0 CH pk, CH, H H N CH -HisH¹-His COO H₂N-CH NH - NH, A biochemist makes up 85 mL of a 0.10 M solution of histidine at a pH of 5.5. She then adds 60 mL of 0.10 M HCI. What is the pH of the resulting solution? CH, H 9.2 C pk CH Macmillan Iraming T im be the [His IM.
Net Charge on an Amino Group.The amino acid glycine has hydrogen as its side-chain (R) group. Values of pKca= 2:36 and pKaa=9:56 have been previously reported for glycine. Superscripts c, a, and s refer to a-carboxylic acid, α-amino base, and side chain, respectively. Using these values, determine the net charge on the a-amino group of glycine at a physiologic pH of 7.2 and a pH of 3 [70].
10. Use the information in the table below to draw the structure of the predominant form of each amino acid at physiological pH (pH = 7.4) R side chain pKa (a-COOH) -CH₂CH(CH3)2 -(CH2)4NH2 -(CH2)2CO2H Amino acid Leucine Lysine Glutamic acid L-leucine L-lysine L-glutamic acid 2.36 2.18 2.19 pKa (α-NH3*) pKa (side chain) 9.60 8.95 9.67 10.79 4.25
25. What is AG for the base hydrolysis of methylamine (CH3NH₂) in water under the following conditions at 25 °C? Kb of CH3NH2 = 4.4 x 10-4 pH = 9.00 [CH3NH3*] = 5.5 x 10-4 M [CH3NH2] = 0.12 M
1. a. Draw the structure of lysine at the following pH's? pka1 (a-COOH) pka2 (α-NH3¹) pka3 (acid side chain) 1) pH = 6.00 2.18 8.95 10.53 11) pH = 9.74
All amino acids have two ionizable functional groups: an a-amino group (average pK, of 9.4) and an a-carboxylic acid group (average pK, of 2.2). Tyrosine also has an ionizable side chain (R group) with a pK, of about 10.1. One of the possible ionization states of tyrosine is shown. H3N-CH -C-OH CH2 ÓH At what pH would the structure be the predominant ionization state? Consider the ionization state of all three of the functional groups. The protonated form of the R group of tyrosine is shown in the structure. The ratio of the protonated form to the charged (deprotonated) form depends on the pK, of the R group and the pH of the solution. Select the pH value at which the charged form of the R group would predominate.
All amino acids have two ionizable functional groups: an α‑amino group (average pKa of 9.4) and an α‑carboxylic acid group (average pKa of 2.2). Aspartic acid has an ionizable side chain (R group) with a pKa of about 3.8. One of the possible ionization states of aspartic acid is shown in the image. At what pH would the structure be the predominant ionization state? Consider the ionization state of all three of the functional groups.
A biochemist completely digests a glycerophospholipid with a mixture of phospholipases A and D. HPLC and mass spectrometry analysis reveals the presence of an amino acid of 105,09 Da, a saturated fatty acid of 256.43 Da, and an omega-3 monounsaturated fatty acid of 282.45 Da. Which amino acid does the glycerophospholipid contain? O valine (C,H, NO,) O alanine (C, H,NO,) O scrine (C,H,NO,) O proline (C,H,NO,) Modify the phosphoglycerol backbone to draw the most likely structure of the lipid. Add the amino acid using the groups tool. Draw Rings Groups More Erase Select
The monoanion of adenosine monophosphate (AMP) is an intermediate in phosphate metabolism: А—О—р—он АMP—ОН- where A = adenosine. If the pKa for this anion is 7.21, what is the ratio of [AMP-OH ] to [AMP-02 ]in blood at pH 7.4?
Glycine is a diprotic acid, which can potentially undergo two dissociation reactions, one for the a-amino group (-NH3), and the other for the carboxyl (-COOH) group. Therefore, it has two pKą values. The carboxyl group has a pK₁ of 2.34 and the a-amino group has a pK₂ of 9.60. Glycine can exist in fully deprotonated (NH₂-CH₂-COO-), fully protonated (NH3-CH₂-COOH), or zwitterionic form (NH3-CH₂-COO-). Match the pH values with the corresponding form of glycine that would be present in the highest concentration in a solution of th pH. fully deprotonated form NH,−CH,−COO- pH 11.9 pH 6.0 pH 8.0 fully protonated form NH3-CH₂-COOH pH 1.0 Answer Bank pH 7.0 zwitterionic form NH3-CH₂-COO-