17. Melittin is a 26-amino acid polypeptide found in bee venom. In its monomeric form, melittin is thought to insert into lipid-rich membrane structures. Explain how the amino acid sequence of melittin accounts for this property. Gly-le-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro 35 hr-Gly-Leu-Pro NH-GIn-Gln-Arg-Lys-Ang-Lys-le-Trp-Ser-le-Leu-Ala

Q: Polypeptide folding is often mediated by other proteins called chaperones. Describe how a mutant…

A: Chaperones are proteins that guide proteins along the proper pathways for folding. They protect…

Q: Two peptide segments are shown below. Predict which one would have the most negative AG when going…

A: Protein folding is a spontaneous reaction by which most of the proteins fold inside the cell without…

Q: Indicate which of the amino acid residues in the following peptide sequence contains a group that…

A: Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon…

Q: A helical wheel is a two-dimensional representation of a helix, a view along its central axis  Use…

A: Amino acids are organic compounds that combine to form proteins.

Q: 1. A simplified structure of the peptide Lys-Glu-Ser with just the ionizable groups in the charged…

A: The given peptide contains two amino groups and two carboxylic groups as ionizable groups. The pKa…

Q: Which peptide would absorb the most UV light at 280nm? (Can you show work because I mainly want to…

A: Aromatic amino acids are relatively non polar.  All aromatic amino acids such as tyrosine,…

Q: An a-Helix (or helices) is often found at anion binding sites of different proteins. Explain this…

A: Helices are spring like structure which forms through the hydrogen bonding between C=O of the ith…

Q: Identify the polar amino acids, the aromatic amino acids,and the sulfur-containing amino acids,…

A: The amino acids are the organic acids that contain alpha carboxyl group, alpha amino group, hydrogen…

Q: Draw the structural formula for the pentapeptide segment being synthesized. (Val-Thr-Arg-Pro-Glu)…

A: Protein is one of the major macromolecules that are essential for the normal functioning of the…

Q: Identify the parts of the heterotrimeric G-protein shown in the image. B

A: Introduction :- G proteins, also known as guanine nucleotide-binding proteins, are a group of…

Q: Kahalalide F NH HN HO NH HN HN O.

A: Proteins are an integral macronutrient that is obtained from the diet. Proteins are formed of amino…

Q: What products are formed when each peptide is treated with trypsin? Be sure to answer all parts.

A: Trypsin is a serine protease belonging to the PA clan that hydrolyzes proteins in the digestive…

Q: w the polypeptide T-R-I-P at pH of 7. Label each residue with the 3-letter code, el the N- and…

A: In a polypeptide chain N terminus is formed by amino group. C terminus  Is formed by carboxyl group

Q: Calculate the pl of the following Peptide

A: At extreme low pH, molecule is fully protonated as the pH increase more than pKa of an ionizable…

Q: 510. Trypsin cleaves proteins after lysine and arginine residues. Trypsin itself has 13 lysine and 2…

A: By cleaving peptide bonds in the protein sequence, protease catalyzes the hydrolysis of proteins…

Q: Consider beta-sheet comprised of twelve amino acid residues (two strands of six residues each). How…

A: Proteins are the macro molecules that show great diversity in their structure. They show four levels…

Q: A tetradecapeptide (14 amino acid residues) gives the following peptide fragments on partial…

A: A peptide is sequence of amino acids in which different amino acids are joined through peptide bond…

Q: A tetrameric protein dissociates into dimers when the detergent sodium dodecyl sulfate (SDS) is…

A: Proteins are polymers of amino acids linked by peptide bonds. Proteins can be single chain or more…

Q: Leu-Glu-Glu-Val-Phe-Ser-Gln-Leu-Cys-Thr-His-Val-Glu-Thr-Leu-Lys a) Circle all of the hydrophilic…

A: Answers to a) and b)Hydrophilic amino acid residues are circled and hydrophobic amino acid residues…