17. A clinical trial is run to assess the efficacy of a new pacemaker device in patients with atrial fibrillation (AF). Two hundred participants are randomized to receive the new pacemaker or a currently available pacemaker. There are two primary outcomes of interest: the number of days in a 3-month period with an atrial fibrillation event, and hospitalization for atrial fibrillation over the 3-month follow-up period. Data on baseline characteristics and the outcomes are shown in Table 6–28. TABLE 6–28 Baseline Characteristics of Participants in Pacemaker Study Baseline Characteristics New Pacemaker (n = 100) Available Pacemaker (n = 100) Mean (SD) age, years 67.3 (5.9) 66.9 (5.6) % Male 48% 52% Outcomes Mean (SD) number of days with AF event 8.4 (3.2) 14.9 (3.9) % hospitalized for AF 4% 9% Compute a 95% confidence interval for the difference in mean number of days with an AF event between participants receiving the new pacemaker as compared to the available pacemaker. Compute a 95% confidence interval for the mean number of days with an AF event among participants receiving the new pacemaker. 18. A clinical trial is run comparing a new drug for high cholesterol to a placebo. A total of 40 participants are randomized (with equal assignment to treatments) to receive either the new drug or placebo. Their total serum cholesterol levels are measured after eight weeks on the assigned treatment. Participants receiving the new drug reported a mean total serum cholesterol level of 209.5 (SD = 21.6) and participants receiving the placebo reported a mean total serum cholesterol level of 228.1 (SD = 19.7). Construct a 95% confidence interval for the difference in mean total serum cholesterol levels between participants receiving the new drug versus placebo. s the new drug effective? Justify briefly.

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

See similar textbooks

Related questions

Question

17. A clinical trial is run to assess the efficacy of a new pacemaker device in patients with atrial fibrillation (AF). Two hundred participants are randomized to receive the new pacemaker or a currently available pacemaker. There are two primary outcomes of interest: the number of days in a 3-month period with an atrial fibrillation event, and hospitalization for atrial fibrillation over the 3-month follow-up period. Data on baseline characteristics and the outcomes are shown in Table 6–28.

TABLE 6–28 Baseline Characteristics of Participants in Pacemaker Study

Baseline Characteristics	New Pacemaker (n = 100)	Available Pacemaker (n = 100)
Mean (SD) age, years	67.3 (5.9)	66.9 (5.6)
% Male	48%	52%
Outcomes
Mean (SD) number of days with AF event	8.4 (3.2)	14.9 (3.9)
% hospitalized for AF	4%	9%

Compute a 95% confidence interval for the difference in mean number of days with an AF event between participants receiving the new pacemaker as compared to the available pacemaker.

Compute a 95% confidence interval for the mean number of days with an AF event among participants receiving the new pacemaker.

18. A clinical trial is run comparing a new drug for high cholesterol to a placebo. A total of 40 participants are randomized (with equal assignment to treatments) to receive either the new drug or placebo. Their total serum cholesterol levels are measured after eight weeks on the assigned treatment. Participants receiving the new drug reported a mean total serum cholesterol level of 209.5 (SD = 21.6) and participants receiving the placebo reported a mean total serum cholesterol level of 228.1 (SD = 19.7).

Construct a 95% confidence interval for the difference in mean total serum cholesterol levels between participants receiving the new drug versus placebo.

s the new drug effective? Justify briefly.

Expert Solution