17) The process mass intensity (PMI) allows chemists to calculate how much material is used when generating a target amount of product in a chemical reaction. PMI is expressed as follows: PMI = [(mass of all input materials)/ (mass of desired product)] %3D To synthesize moclobemide, an anti-depressant pharmaceutical, 0.00381 moles of 4-(2-aminoethyl)morpholine (CoH14N20) is dissolved in 20.0 ml-of triethylamine (density: 0.726 g mlL-) and 0.00384 moles of 4-chlorobenzoyl chloride (C-H.Cl20) is added. After rapid stirring for 30 minutes, 10.0 mL (density: 1.00 g mL-) of water is added followed by 10.0 mL of dichloromethane (density: 1.325 g mL-) and then the mixture transferred to a separatory funnel. After extraction, the dichloromethane is dried with 5.0 g of magnesium sulfate. At the end of the process, 0.826 g of pure moclobemide is recovered. The PMI for this reaction is: A) 43.8 B) 47.1 C) 49.3 D) 53.2 E) 55.9
17) The process mass intensity (PMI) allows chemists to calculate how much material is used when generating a target amount of product in a chemical reaction. PMI is expressed as follows: PMI = [(mass of all input materials)/ (mass of desired product)] %3D To synthesize moclobemide, an anti-depressant pharmaceutical, 0.00381 moles of 4-(2-aminoethyl)morpholine (CoH14N20) is dissolved in 20.0 ml-of triethylamine (density: 0.726 g mlL-) and 0.00384 moles of 4-chlorobenzoyl chloride (C-H.Cl20) is added. After rapid stirring for 30 minutes, 10.0 mL (density: 1.00 g mL-) of water is added followed by 10.0 mL of dichloromethane (density: 1.325 g mL-) and then the mixture transferred to a separatory funnel. After extraction, the dichloromethane is dried with 5.0 g of magnesium sulfate. At the end of the process, 0.826 g of pure moclobemide is recovered. The PMI for this reaction is: A) 43.8 B) 47.1 C) 49.3 D) 53.2 E) 55.9
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Chapter1: Chemical Foundations
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![17) The process mass intensity (PMI) allows chemists to calculate how much
material is used when generating a target amount of product in a chemical
reaction. PMI is expressed as follows:
2
PMI = [(mass of all input materials)/ (mass of desired product)]
To synthesize moclobemide, an anti-depressant pharmaceutical,
0.00381 moles of 4-(2-aminoethyl)morpholine (CoH14N20) is dissolved in
20.0 ml-of triethylamine (density: 0.726 g mL-1) and 0.00384 moles of
4-chlorobenzoyl chloride (C-H.Cl20) is added. After rapid stirring for
30 minutes, 10.0 mL (density: 1.00 g mL-1) of water is added followed by
10.0 mL of dichloromethane (density: 1.325 g mL-1) and then the mixture
transferred to a separatory funnel. After extraction, the dichloromethane is
dried with 5.0 g of magnesium sulfate. At the end of the process, 0.826 g of
pure moclobemide is recovered.
The PMI for this reaction is:
A) 43.8
B) 47.1
C) 49.3
D) 53.2
E) 55.9](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fa9bdae71-8d7d-47f9-ace9-0cd1164e3dd6%2F82d2aaf9-b4b6-425f-9043-ff8d0bc40b45%2Foppxnv_processed.jpeg&w=3840&q=75)
Transcribed Image Text:17) The process mass intensity (PMI) allows chemists to calculate how much
material is used when generating a target amount of product in a chemical
reaction. PMI is expressed as follows:
2
PMI = [(mass of all input materials)/ (mass of desired product)]
To synthesize moclobemide, an anti-depressant pharmaceutical,
0.00381 moles of 4-(2-aminoethyl)morpholine (CoH14N20) is dissolved in
20.0 ml-of triethylamine (density: 0.726 g mL-1) and 0.00384 moles of
4-chlorobenzoyl chloride (C-H.Cl20) is added. After rapid stirring for
30 minutes, 10.0 mL (density: 1.00 g mL-1) of water is added followed by
10.0 mL of dichloromethane (density: 1.325 g mL-1) and then the mixture
transferred to a separatory funnel. After extraction, the dichloromethane is
dried with 5.0 g of magnesium sulfate. At the end of the process, 0.826 g of
pure moclobemide is recovered.
The PMI for this reaction is:
A) 43.8
B) 47.1
C) 49.3
D) 53.2
E) 55.9
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