11. Below is a table from the journal article "“Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function Detected at Quantitative MRI" by Caporale, et. al. from Radiology 2019. Nonsmokers were asked to inhale nicotine-free e-cigarette aerosol, and variables were measured. Effects of Electronic Cigarette Aerosol Inhalation.on Vascular Function Table 4: Comparisons before and after E-cigarette Vaping MRI Parameters Before E-cigarette Vaping After E-cigarette Vaping PValue Peripheral vascular reactivity Dynamic superficial femoral vein oximetry (SvO,) Baseline SvO, (%HbO,) Washout time (sec) Upslope (%HbO./sec) Overshoot (9%HbO,) Peak-to-peak SvO, (%HbO,) Superficial femoral artery blood flow velocity Resistivity index Peak velocity (cm/sec) Time to peak (sec) Hyperemic index (cm/sec) Vessel wall imaging FMD, (%) Cetcbrovascular reactivity Breath-hold index (cm/sec) Post-breath hold relative velocity increase (%) Central arterial stiffness aPWV (m/sec) 65 2 52 2 <.001 9.1 04 7.6 0.2 .001 3.0 0.2 3.0 0.2 29 2 41 2 61 19 2 <.001 40 2 49 1.30 0.01 56.6 26 7.1 0.6 1.33 0.01 46.7 28 9.20.7 11.2= 0.9 04 .001 .005 15.1 1.1 <001 9.4 0.9 6.2 0.9 001 0,38 0.02 31.2 2.1 0.36 0.02 35.7 23 08 10 6.05 + 0.21 6.24 0.20 Las Note-Data are mean standard error. Upslope refers to the slope of curve following nadir, overshoor refers to the maximum SvO, rele tive to bascline SvO, aPWV-aortic arch pulse wave velocity, FMD, - luminal flow-mediated dilation, SvO venous oaygen saturation a.) Who is the target population (be specific)? b.) Assuming the statistical tests were run correctly, fill in the following for determining at a = .05 whether a difference can be shown in the true means for "breath-hold index" measured in cm/ sec2 with respect to cerebrovascular reactivity.

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11. Below is a table from the journal article "Acute Effects of Electronic Cigarette Aerosol Inhalation on
Vascular Function Detected at Quantitative MRI" by Caporale, et. al. from Radiology 2019. Nonsmokers
were asked to inhale nicotine-free e-cigarette aerosol, and variables were measured.
Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function
Table 4: Comparisons before and after E-cigarette Vaping
MRI Parameters
Before E-cigarette Vaping
After E-cigarette Vaping
P Value
Peripheral vascular reactivity
Dynamic superficial femoral vein oximetry (SvO,)
Baseline SvO, (96HBO,)
Washout time (sec)
52 2
7.6 0.2
65 2
<.001
9.1 0.4
3.0 0.2
19 2
.001
Upslope (96H60 /sec)
Overshoot (%HbO,)
Peak-to-peak SvO, (%HbO_)
Superficial femoral artery blood flow velocity
Resistivity index
Peak velocity (cm/sec)
Time to peak (sec)
Hyperemic index (cm/sec)
Vessel wall imaging
FMD, (%)
Cerebrovascular reactivity
Breath-hold index (cm/sec)
Post-breath hold relative velocity increase (%)
Central arterial stiffness
aPWV (m/sec)
3.0 0.2
61
29 2
<.001
40 ± 2
41 ± 2
49
1.33 0.01
46.7 2.8
9.2 0.7
11.2 0.9
1.30 0.01
04
56.6 t 2.6
<.001
7.1 ± 0.6
.005
15.1 1.1
<.001
9.4 0.9
6.2 0.9
<.001
0.36 0.02
35.7 2.3
0.38 0.02
.08
31.2 ± 2.1
.10
6.05 0.21
6.24 0.20
,05
Note-Data are mean standard error. Upslope refers to the slope of curve following nadir; overshoot refers to the maximum SvO, rela-
tive to baseline SvO, aPWV = aortic arch pulse wave velocity, FMD, = luminal flow-mediated dilation, SvO,- venous oxygen saturation.
I
a.) Who is the target population (be specific)?
b.) Assuming the statistical tests were run correctly, fill in the following for determining at a =
.05 whether a difference can be shown in the true means for "breath-hold index" measured in cm/
sec2 with respect to cerebrovascular reactivity.
Transcribed Image Text:11. Below is a table from the journal article "Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function Detected at Quantitative MRI" by Caporale, et. al. from Radiology 2019. Nonsmokers were asked to inhale nicotine-free e-cigarette aerosol, and variables were measured. Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function Table 4: Comparisons before and after E-cigarette Vaping MRI Parameters Before E-cigarette Vaping After E-cigarette Vaping P Value Peripheral vascular reactivity Dynamic superficial femoral vein oximetry (SvO,) Baseline SvO, (96HBO,) Washout time (sec) 52 2 7.6 0.2 65 2 <.001 9.1 0.4 3.0 0.2 19 2 .001 Upslope (96H60 /sec) Overshoot (%HbO,) Peak-to-peak SvO, (%HbO_) Superficial femoral artery blood flow velocity Resistivity index Peak velocity (cm/sec) Time to peak (sec) Hyperemic index (cm/sec) Vessel wall imaging FMD, (%) Cerebrovascular reactivity Breath-hold index (cm/sec) Post-breath hold relative velocity increase (%) Central arterial stiffness aPWV (m/sec) 3.0 0.2 61 29 2 <.001 40 ± 2 41 ± 2 49 1.33 0.01 46.7 2.8 9.2 0.7 11.2 0.9 1.30 0.01 04 56.6 t 2.6 <.001 7.1 ± 0.6 .005 15.1 1.1 <.001 9.4 0.9 6.2 0.9 <.001 0.36 0.02 35.7 2.3 0.38 0.02 .08 31.2 ± 2.1 .10 6.05 0.21 6.24 0.20 ,05 Note-Data are mean standard error. Upslope refers to the slope of curve following nadir; overshoot refers to the maximum SvO, rela- tive to baseline SvO, aPWV = aortic arch pulse wave velocity, FMD, = luminal flow-mediated dilation, SvO,- venous oxygen saturation. I a.) Who is the target population (be specific)? b.) Assuming the statistical tests were run correctly, fill in the following for determining at a = .05 whether a difference can be shown in the true means for "breath-hold index" measured in cm/ sec2 with respect to cerebrovascular reactivity.
11. a.) Target popln.
b.) Ho
На
Dec.
Concl.
p-value
SIG or NS
Transcribed Image Text:11. a.) Target popln. b.) Ho На Dec. Concl. p-value SIG or NS
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