10. Select reagents from the table to show how you would carry out these transformations. You should use no more than 3 steps. Enter your selection as a series of letters for the reagents in the order you would use them. HINT: Each requires 4 steps. The first step in these two syntheses requires either a 1,4-addition or allylic bromination. Reagents a. C. d. H2. Pd/C Br₂, CH2Cl2 b. KCN, HCN LiAlH4 then H₂O* e. excess NBS, CC₁₁ f. excess CH3MgBr, ether then H₂O* g. H₂O*, heat H3CCH=CHCH3 a. H₂NCH2CH2CH2CH2CH2CH2NH2
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
transformations. You should use no more than 3 steps. Enter your
selection as a series of letters for the reagents in the order you would
use them.
HINT: Each requires 4 steps. The first step in these two syntheses requires
either a 1,4-addition or allylic bromination.
a.
KMnO4 / H3O+
KMnO4 / H3O+
Step by step
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