The following synthesis requires more than one step. Specify the reagents you would use to carry it out. (Specify reagents using letters from the table, first reagent on the left. Example: ab) (Notice that there are two possibilities given: NaNH2, and NaNH2 in combination with water.) Reagents available a. Br₂ e. D₂0 b. 3 NaNH / NH3 then H,O f. 2 NaNH,/NH3 c. NaNH, / NH3 g. CH3CH2I d. CH3 CH₂ CH₂ Br
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![**Synthesis Reaction Exercise**
The following synthesis requires more than one step. Specify the reagents you would use to carry it out.
*(Specify reagents using letters from the table, first reagent on the left. Example: ab)*
![Synthesis Reaction Diagram]
*Diagram depicting a linear alkene transforming into an alkyne structure.*
*(Notice that there are two possibilities given: NaNH₂ and NaNH₂ in combination with water.)*
**Reagents Available**
- **a.** Br₂
- **b.** 3 NaNH₂ / NH₃ then H₂O
- **c.** NaNH₂ / NH₃
- **d.** CH₃CH₂CH₂Br
- **e.** D₂O
- **f.** 2 NaNH₂ / NH₃
- **g.** CH₃CH₂I
**The reagents are (in order of use):** [____]](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd72a3123-7c63-4e48-96b9-2d394375b3c8%2F2ab947f8-f8af-41b7-8134-96ed1695d970%2Ftaagkoh_processed.jpeg&w=3840&q=75)
In the given organic reaction, an alkene (compound with double bond) is an alkyne (compound with triple bond).
Identify the correct set of targets for the above conversion:
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