1. The gold standard for RMSF( Rocky Mountain Spotted Fever) is IFA (indirect immunofluorescence assay). Describe the specimen handling and expected results to establish RMSF.

Human Anatomy & Physiology (11th Edition)
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Immunology Questions

1. The gold standard for RMSF( Rocky Mountain Spotted Fever) is IFA (indirect immunofluorescence assay). Describe the specimen handling and expected results to establish RMSF.


2. Why is it important to test for both IgM and IgG titers with the IFA test for RMSF?


3. What titer level is indicative of acute infection with Babesiosis?


4. What two diagnostic tests should be used during the acute stage of illness caused by Human Ehrlichiosis?


5. What single titer level is a confirmation of anaplasmosis?

6. A request is received in the laboratory for selection of the appropriate tests for detecting Lyme disease. Which of the following would you suggest?

a. stool culture to isolate the causative organism

b. comparing antibody titers

c. isolation of Borelia burgdorferi from blood cultures

d. this is an immunologic syndrome, cultures are not indicated

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