1. The following reactions can be coupled in the citrate cycle. kJ/mol kJ/mol Succinyl-CoA GDP + Pi. succinate + CoA GTP G=-34.0 Gº= 30.5 a) Write the net reaction. Calculate Gº for the coupled reaction. Is the reaction favorable? b) Write the equilibrium constant in terms of reactant and product concentration. Calculate the equilibrium constant, K, for the coupled reaction at 37°C. c) If the ratio of [GTP/[GDP] in the cell is 22, the [CoA]/[succinyl-CoA] ratio is 0.20, and the [Pi] is 1.3mM, determine the [Succinate] at equilibrium. (Pay attention to concentration units)

1. The following reactions can be coupled in the citrate cycle. kJ/mol kJ/mol Succinyl-CoA GDP + Pi. succinate + CoA GTP G=-34.0 Gº= 30.5 a) Write the net reaction. Calculate Gº for the coupled reaction. Is the reaction favorable? b) Write the equilibrium constant in terms of reactant and product concentration. Calculate the equilibrium constant, K, for the coupled reaction at 37°C. c) If the ratio of [GTP/[GDP] in the cell is 22, the [CoA]/[succinyl-CoA] ratio is 0.20, and the [Pi] is 1.3mM, determine the [Succinate] at equilibrium. (Pay attention to concentration units)

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Related questions

Q: Use the information provided to fill out the table: 1- They will use the information from the…

A: The following case study explores the anesthetic approach for a 13-year-old, 8.8 kg mixed-breed male…

Q: Explain the ethical considerations nurses should be prepared to address with patients as they…

A: • Cystic fibrosis is a fatal genetic disorder impacting multiple body systems. • Abnormal transport…

Q: II The pedigree above tracks the presence of attached earlobes through a family's generation. Having…

A: As per our policy we are answering the only one question. For the rest of the question kindly…

Q: acronym:

A: An acronym is a kind of word that is produced by abbreviating a term by linking specific letters of…

Q: Are there other legitimate means that can be used as a substitute for the polygraph test? Do these…

A: Polygraph test or more popularly known as lie detector test uses several parameters and test to…

Q: Based on this video: https://youtu.be/3PYdMaClUmw Observation Interpretation Test Tube…

A: Chemical reactions in living cells are catalyzed by enzymes.

Q: Part III-PGD? Suzanne and David decided to have children. They wanted to ensure that their children…

A: NOTE: according to the answering guidelines, I am going to answer only first question. Please post…

Q: Using the information provided, fill out the table: 1- They will use the information from the…

A: The following case study explores the anesthetic approach for a 13-year-old, 8.8 kg mixed-breed male…

Q: Multiplexing agglutination

A: Multiplex assays, a type of immunoassay which constitutes of tests in which magnetic beads are used…

Q: As a health advocate for migrant workers, what federal health laws would you rely on in addressing…

A: Federal Health Laws and Protections for Migrant WorkersMigrant workers play a crucial role in…

Q: Structural hierarchy Complete each statement below and then place them in order from smallest to…

A: Levels of organization from simple to complex forms: Let us first define the terms given in the left…

Q: A man with blood type A marries a woman with blood type B. Their child has blood type O. What are…

A: Blood group Blood group of human being is a genetic character. There are four type of human blood…

Q: _cells stimulate both arms of the immune response (one arm is self and the other arm is foreign)

A: According to guideliness we have to answer the first question only so please kindly post the 2nd…

Q: Explain how familial retinoblastoma is inherited at the: a. Čellular level Vs. b. The pedigree level…

A: The cells of the retina of the eye are where retinal blastoma begins. A mass of cancer cells known…

Q: /hich type of colorectal cancer is considered to be an autosomal dominant disorder haracterized with…

A: Colorectal cancer is any cancer that affects the colon and the rectum. It acts as a growth on the…

Q: I am having trouble conducting a search for articles for this PICOT question. I would like to use…

A: You can improve the precision and clarity of your PICOT inquiry. I'll also provide some criticism…

Q: 1. The MN blood system is inherited as an autosomal trait showing codominance. The genotype LMLM…

A: A population represents a group of individuals of the same species that live together.

Q: Brief summary of what the document that is in the link is about…

A: Veterinary dental radiology refers to the use of radiography techniques to capture images of a pet's…

Q: Please help True or false, if false rewrite the statement in a way that makes it true. a) A cell…

A: A cell can be defined as the basic structural, functional, and biological unit of all known living…

Q: An insecticide is a chemical that can rid a plant of insects that cause damage to the plant. If the…

A: Plant breeding and development of different pesticides are very important and critical in…

Q: QUESTION 1) Scientists have been studying a population of dragonflies of a remote island in an…

A: Note: Since you have asked three questions and all three are not interrelated, the first one has…

Q: Segmentation 1. 2. 234 3. 4. 1. 2. 3. 4. Metamerism

A: segmentation metamerism 1) it is process in which organism is divided into two or more parts but…

Q: What is a carcinoma in situ (CIS)? Edit View Insert Format Tools Table 12pt v Paragraph v d to…

A: Carcinoma in situ is a group of abnormal cells which have not spread beyond the place of their…

Q: Please write your complete solution (paper). Albinism in humans is inherited as a simple recessive…

A: Alleles at the alternative forms of a gene that are located on the same locus of a homologous…

Question

Please explain each part thoroughly with explanations and answers given. This is Bipchemistry

1. The following reactions can be coupled in the citrate cycle.
kJ/mol
kJ/mol
Succinyl-CoA
GDP + Pi.
succinate+CoA
GTP
Gº=-34.0
Gº= 30.5
a) Write the net reaction. Calculate Gº for the coupled reaction. Is the reaction favorable?
b) Write the equilibrium constant in terms of reactant and product concentration. Calculate the equilibrium constant,
K, for the coupled reaction at 37˚C.
c) If the ratio of [GTP/[GDP] in the cell is 22, the [CoA]/[succinyl-CoA] ratio is 0.20, and the [Pi] is 1.3mM,
determine the [Succinate] at equilibrium. (Pay attention to concentration units)
d) If the [GTP/[GDP] falls to 2.0, calculate G, keeping all other concentrations the same including succinate from
above. If the [GTP/[GDP] increases to 100, calculate []G, keeping all other concentrations the same.
e) What conclusion can you reach about the direction of the reaction under these cellular conditions? Is this reaction
reversible or irreversible?

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1: Citrate cycle

Step 2: Answer 1 a)

Step 3: Answer 1 b)

Step 4: Answer 1 c)

Solution

Trending now

This is a popular solution!

Step by step

Solved in 5 steps

SEE SOLUTION Check out a sample Q&A here

Similar questions

What cause of the genetic disease site your sources provide links to the websites to use?
a Unit +. A virtuallearningacademy.net/vla/Student/LessonRead.aspx?H=Q&L=10204&C=224325&S=101494&CS=659537 COMMUNITY SsCHOOL, 207 LOWELL STREET, CASTALIA, OH, 44824 419-684-5402 Course: SCI Biology Unit: Unit 23: Heredity Sex-Linked 14) In Morgan's second experimental cross of fruit fly eye color, what was the phenotype of the F2 generation? OA.) 100% Red eyes OB.) 50% Red eyes; 50% white eyes OC.) 3 Red eyes to 1 white eyes Save 15) What gender is more likely to have any sex-linked trait? OA.) female ов.) male OC.) neither Save 16) Fruit Fly Eye Color (sex-linked): Red Eye (Dominant - R), White Eye (Recessive - r): How many female fruit fly offspring would be expected to have white eyes from the following cross? Parents: White Eye Female x Red Eye Male OA.) 0% ов.) 25% OC.) 50% Save
For this statement, answer True or False and explain your answer briefly. In the mitochondrial DNA analysis, it is necessary to analyze and record the whole DNA sequence for personal identification.
6) prefixes may be used to indicate direction or body position. A) true B) False
Give typed explanation of all not a single word hand written otherwise leave it A tortoiseshell cat is found with two kittens. One of the kittens is an orange female, and the other kitten is a black male. What would be the genotype of the tortoiseshell cat (the mother of the two kittens)? ____________________________ What would be the genotype of the male cat that fathered the two kittens? ____________________________ Draw a Punnett square in the space below, showing the potential genotypes of kittens produced by a cross between the tortoiseshell cat and the father of the two kittens.
List and explain each color portion of the line on the graph above. Line Color Stage of Infection Description Blue Green Pink Orange Purple
What is the structure highlighted?The options are the second picture. thank you.
According to the video, how do anthropologists study the Egyptian Mummies? Video - https://www.youtube.com/watch?v=mQrbFxgDi9I a. Mummy unwrapping and autopsiesb. CT scanningc. Blood testsd. All the above
edmentum.com/assessments-delivery/ua/mt/launch/88343/45384918/aHROcHM6Ly9mMiShcHAuZWRtZW50dWouY29tL2xlYXJuZXltdWkvc2Vjb25kYXJ51 Mitosis and Meiosis: Mastery Test Drag each tile to the correct location. Sort the descriptions based on whether they are related to mitosis or meiosis. creates two creates four creates haploid cells creates diploid cells identical cells nonidentical cells occurs in all cells occurs in cells related other than gametes to sexual reproduction Mitosis Meiosis reserved.
i need an abstract style (something you would submit to an academic conference) summary/introduction/presentation of this case study?
Identify the following table. List the salient features (5-6) of this table.
Type with keyboard, writing not clear