A 2-and-a-half-year-old kid who weighed 11kg and had no previous/ known medical conditions was hospitalised for various bruises for one week owing to thrombocytopenia. Immune thrombocytopenic purpura was identified as the cause. In light of bleeding manifestations and extremely severe thrombocytopenia with platelet level of 3 109/L, patient was suggested for two units of whole blood, derived platelet transfusion and began on intravenous immunoglobulin at a dose of 1 mg/kg. Due to the lack of blood group B platelets, the patient, who is B Rhesus D positive, got O RhD positive WB-derived platelets. During the second unit of platelet transfusion, the kid started to experience, shortness of breath, chill, and rigor. the patient became worse with a fever of 38 C,
A 2-and-a-half-year-old kid who weighed 11kg and had no previous/ known medical conditions was hospitalised for various bruises for one week owing to thrombocytopenia. Immune thrombocytopenic purpura was identified as the cause.
In light of bleeding manifestations and extremely severe thrombocytopenia with platelet level of 3 109/L, patient was suggested for two units of whole blood, derived platelet transfusion and began on intravenous immunoglobulin at a dose of 1 mg/kg. Due to the lack of blood group B platelets, the patient, who is B Rhesus D positive, got O RhD positive WB-derived platelets.
During the second unit of platelet transfusion, the kid started to experience, shortness of breath, chill, and rigor. the patient became worse with a fever of 38 C, an oxygen saturation of 80% in room air, hypotension (94/56 mmHg), tachycardia (156 beats/minute), and tachypnea (26 breaths/minute).
Blood film evidence of spherocytosis and tiny agglutinations helped to explain why the patient's haemoglobin fell from 10.2 g/dl to 8.2 g/dl. The kid's lactate dehydrogenase levels were 1209 U/L and had a minor case of jaundice. The erythrocytes showed that the Direct Antiglobulin Test was positive.
Critically explain how to reach the final diagnosis/what the find diagnosis is looking at the information and details given, and what could have caused the symptoms for the patient.
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can you get a bit more in-depth with how you have reached the final diagnosis and the factors mentioned above?
by Bartleby Experti need an abstract style (something you would submit to an academic conference) summary/introduction/presentation of this case study?
by Bartleby Expertwhat could be the possible cause of this condition? what are the underlying principles? and why the patient would experience these exact symptoms?
by Bartleby Expertwhat are the limitations of the above-mentioned tests for this condition?
by Bartleby Expertwhat are the key pathophysiological findings of this condition?
by Bartleby Expertwhat would some effective treatments be for this condition?
by Bartleby Expertwhat are some treatments and controls for this condition as well as tests?
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