1. The dramatic reaction below was reported in the Evans synthesis of colchicine in 1981. MeO CO₂Me -CO₂Me OH MeO OMe CF3CO₂H MeO 5 3 OMe MeO OMe OMe A. Label reactant carbon atoms 1-7 in the product and circle the single bond made in the product through an electrophilic aromatic substitution process. B. Add curved arrows and a reactive intermediate below to show how the starting materials of this reaction convert to intermediate A via 1. pt; 2. [AE + SN2]. CO₂Me OH MeO. OMe MeO F3CCO₂ H [AE + SN2] OMe pt MeO MeO OMe A -CO₂Me -OH OH OMe -O₂CCF3

1. The dramatic reaction below was reported in the Evans synthesis of colchicine in 1981. MeO CO₂Me -CO₂Me OH MeO OMe CF3CO₂H MeO 5 3 OMe MeO OMe OMe A. Label reactant carbon atoms 1-7 in the product and circle the single bond made in the product through an electrophilic aromatic substitution process. B. Add curved arrows and a reactive intermediate below to show how the starting materials of this reaction convert to intermediate A via 1. pt; 2. [AE + SN2]. CO₂Me OH MeO. OMe MeO F3CCO₂ H [AE + SN2] OMe pt MeO MeO OMe A -CO₂Me -OH OH OMe -O₂CCF3

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Can someone show me the complete mechanism with arrows? How would the reaction be different if no heat was added?
Draw the product of the reaction
#19 help
I need help with this
Identify the correct reagents and conditions to perform this chemoselective reaction: H ရှုံး H Select one: Me e. Reagent(s) and conditions? a. NaBH4 b. BH3 THF Pd/BaSO4, H₂ (1 atm.), quinoline, Pb(OAC)2, MeOH d. Pd/C, H2 (1 atm.), MeOH DIBAL Me H H OH
Draw the products of the reaction shown below. Ignore inorganic byproducts. O₂N. cat. H₂SO4 O HNO3 (1 equiv) Drawing
For the Michael reaction shown below, which is the appropriate base to use for this reaction? base OCH3 + CH;OČCH,ÖCH3 H3C° O HO O CH3CH2O¯ O CH3O- O base is unnecessary as this is an acid-catalyzed reaction O any hydroxide or alkoxide base will work
3. The reaction below produces mainly compound W. Draw the structure of W. Me OH gue- trace H OH W
In each of the following pairs, indicate which has a higher concentration of 1- ion: a. 0.10 M BaI2 or 0.25 M KI solution b. 100 mL of 0.10 M KI solution or 200 mL of 0.40 M ZnI2 solution c. 3.2 M HI solution or a solution made by dissolving 145 g of NaI in water to make 150 mL of solution