1. The antibacterial activity of flavonoids was tested against the bacterial strain, Escherichia coli. The minimum inhibitory concentration at which 50% of the compounds were inhibited (MIC50) are presented in the table below for some of the compounds. Table 1: Antibacterial activity of flavonoids tested against E. coli Compound Kaempferol Quercetin Compound X Luteolin Tangeritin 5,6,7,4'- Tetramethoxyflavone Genistin Genistein MIC50 (µg/mL) 25.50 35.76 36.72 67.25 137.10 156.34 238.94 320.88 1.3 Would myricetin have higher or lower antibacterial activity compared to quercetin? Justify your answer by using the results provided.

1. The antibacterial activity of flavonoids was tested against the bacterial strain, Escherichia coli. The minimum inhibitory concentration at which 50% of the compounds were inhibited (MIC50) are presented in the table below for some of the compounds. Table 1: Antibacterial activity of flavonoids tested against E. coli Compound Kaempferol Quercetin Compound X Luteolin Tangeritin 5,6,7,4'- Tetramethoxyflavone Genistin Genistein MIC50 (µg/mL) 25.50 35.76 36.72 67.25 137.10 156.34 238.94 320.88 1.3 Would myricetin have higher or lower antibacterial activity compared to quercetin? Justify your answer by using the results provided.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: Draw the structures of the substrate (pNPP) and of the inhibitors (Pi and Phe). Consider them in the…

Q: What advantage does the enzyme gain by forming an imine?

A: Now when we consider a carbonyl compound which undergoes tautomerism to form enol under the…

Q: How do NSAIDs prevent production of prostaglandins? O changing their chemical structure and…

A: NSAIDs stands for non steroidal anti-inflammatory drug. It usually used to get relief from…

Q: help please answer in text form with proper workings and explanation for each and every part and…

A: Approach to solving the question: Detailed explanation: Examples: Key references:

Q: Meat is refrigerated to prevent spoilage by bacteria because the cold A. denatures bacterial…

A: Temperature changes the activity of the enzyme . There is the optimum temperature where the enzyme…

Q: d) 1.EtMgBr. 2. HО PCC CH2Cl2 A

Q: Determine whether each of the inhibitors (or inhibitor characteristics) are involved in reversible…

A: Enzyme Inhibition - The rate of enzyme catalyzed reactions are decreased due to addition of…

Q: 3. Some medications permanently inactivate their target enzyme by forming a covalent bond to an…

A: Given, drug is penicillin. The structure of penicillin is shown below: The active site in…

Q: Vitamin C activity is present in D-Dehydroascorbic acid Both D-Ascorbic acid and D- Dehydroascorbic…

A: The activity of Vitamin C is present in L-ascorbic acid.

Q: 10. Factor In the enzyme catalyzed reaction depicted above, which factor could be changed…

A: Inhibitor: An inhibitor will decrease the rate of reaction by decreasing the activity of the…

Q: What do you predict the addition of a base will have on catalase? Will it increase, decrease, or…

A: Catalase is a key enzyme which uses hydrogen peroxide, a nonradical ROS, as its substrate. This…

Q: The graph shows how the rate of an enzyme-catalyzed reaction depends on the variable x. Which of the…

A: A question based on reaction rate. The most appropriate x-axis from the available options is chosen…

Q: Note the Myoglobin O₂ binding curve below. YO2 1.00 0.80 0.60 0.40 0.20 0.0 Myoglobin O₂ Binding…

Q: Explain the relationship between structure and activity of beta-Lactamase Inhibitors derivative…

A: Antibiotic, a medicine that inhibit the growth of microorganisms.

Q: Which of the following produce heat 1 - labile enterotoxin which can be damaged by food boiling 1…

A: The question is asking us to identify which of the given bacteria produce a heat-labile enterotoxin.…

Q: Determine whether each of the inhibitors (or inhibitor characteristics) are involved in reversible…

A: Inhibitors are those compounds that can reduce the activity of an enzyme. They can reduce the…

Q: help please answer in text form with proper workings and explanation for each and every part and…

A: Step 1:In the presence of the enzyme urease at pH 8.0 and 20°C, the reaction rate is increased by…

Q: In a cell, the activation energy needed for a reaction to occur is likely lowered b a localized…

A: Activation energy is the minimum amount of extra energy required by a reacting molecule to get…

Q: How does aqueous Silver nitrate, AGNO3, works against neonatal conjunctivitis (inflammation of the…

Q: What amino acid can heal/nourish the cells of the small intestine (as we Taurine Leucine Glutamine…

A: Glutamine

Q: This cartoon depicts which type of enzyme inhibition? inhibitor substrate. - products no reaction A)…

A: An enzyme inhibitionAn enzyme inhibitor is a substance that prevents an enzyme from reacting with…

Q: temperature do you think the enzyme will function optimally

Q: The disease Phenylketonuria (or PKU) occurs when the enzyme that helps to catalyze the conversion of…

A: Hello. Since your question has multiple parts, we will solve the first question for you. If you want…

Concept explainers

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.

Question

1. The antibacterial activity of flavonoids was tested against the
bacterial strain, Escherichia coli. The minimum inhibitory
concentration at which 50% of the compounds were inhibited
(MIC50) are presented in the table below for some of the
compounds.
Table 1: Antibacterial activity of flavonoids tested against E.
coli
Compound
Kaempferol
Quercetin
Compound X
Luteolin
Tangeritin
5,6,7,4'-
Tetramethoxyflavone
Genistin
Genistein
MIC50 (µg/mL)
25.50
35.76
36.72
67.25
137.10
156.34
238.94
320.88
1.3 Would myricetin have higher or lower antibacterial activity
compared to quercetin? Justify your answer by using the results
provided.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Given

VIEW

Answer

VIEW

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

What is the relationship between the zone of inhibition and the antibiotic concentration? Is it inversely proportional or directly proportional to each other?
Neostigmine is an inhibitor of acetylcholinesterase. The enzyme attempts to catalyse the same reaction on neostigmine as it does with acetylcholine. However, a stable intermediate is formed which prevents completion of the process and which results in a molecule being covalently linked to the active site. Identify (draw) the stable intermediate and explain why it is stable.
The substance where the enzyme reacts with? A. Substrate B. Inhibitor C. A & B D. Activator E. Product
Triosephosphate isomerase (TIM) catalyzes the conversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate. The enzyme’s catalytic groups are Glu 165 and His 95. In the first step of the reaction, these catalytic groups function as a general-base and a general-acid catalyst, respectively. Propose a mechanism for the reaction.
Predict the product(s) obtained when each of the following compounds is treated with a mixture of nitric acid and sulfuric acid. Select all that apply. 18.41d * Your answer is incorrect.
Trypsin is a serine protease that has a KM of 15 mM. At an initial substrate concentration of 250 µM insulin, trypsin is found to degrade insulin at a rate of 0.6 µM/min. If the concentration of trypsin in solution was 4.326 µM, what is the kcat of trypsin in s-1?
Each compound was tested for its ability to inhibit fatty acid synthase activity in both normal cells and breast cancer cells. ID50 values (the inhibitor concentration required to inhibit cell growth by 50%) are shown in the table. Which inhibitors are most effective? Compound Alkyl side chain (R) Breast cancer cellsID50 (µg/mL) Normal cellsID50 (µg/mL) A −−C13H27 3.9 10.6 B −−C11H23 4.8 29.0 C −−C8H17 5.0 21.3 D −−C6H13 8.4 12.4 Compound D Compound C Compound A Compound B
Why can't insulin be taken orally? It does not taste very good Enzymes in saliva break it down Hydrolysis of insulin occurs in the stomach It is not possible to store insulin
which NFPA label correctly describes diethyl ether (CH3CH2)2O
If the vaccine effectiveness towards providing protection from hospitalization is 90% which of the following statements is true If you are vaccinated your chance of becoming hospitalized is 10% If you are unvaccinated your chance of becoming hospitalized is 90% The rate of hospitalization among vaccinated people is 10% of the rate of hospitalization among unvaccinated people The rate of hospitalization among vaccinated people is 90% of the rate of hospitalization among unvaccinated people
Explain the principle involved in the drug receptor interaction of a drug
5. Why are some drugs given in combination, provide a suitable example