**Text Transcription:**1. Suggest a reasonable series of synthetic transformations (i.e., a series of reagents and reaction conditions) to prepare cis-2-methylcyclohexyl acetate (A) from trans-2-methylcyclohexanol.**Explanation of the Diagram:**The diagram shows a chemical structure labeled "A (target molecule)." The structure represents cis-2-methylcyclohexyl acetate. It features a cyclohexane ring with a methyl group (\( \text{CH}_3\)) attached at the second position. The acetate group, identified by the \( \text{OCOCH}_3 \) side chain, is also attached to the ring. The notation of "cis" indicates the arrangement of different groups on the same side of the cyclohexane ring.

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1. Suggest a reasonable series of synthetic transformations (i.e. a series of reagents and reaction conditions) to prepare cis-2-methylcyclohexyl acetate (A) from trans-2- methylcyclohexanol H,C CH3 A (target molecule)

1. Suggest a reasonable series of synthetic transformations (i.e. a series of reagents and reaction conditions) to prepare cis-2-methylcyclohexyl acetate (A) from trans-2- methylcyclohexanol H,C CH3 A (target molecule)

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

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Concept explainers

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.

Question

**Text Transcription:**

1. Suggest a reasonable series of synthetic transformations (i.e., a series of reagents and reaction conditions) to prepare cis-2-methylcyclohexyl acetate (A) from trans-2-methylcyclohexanol.

**Explanation of the Diagram:**

The diagram shows a chemical structure labeled "A (target molecule)." The structure represents cis-2-methylcyclohexyl acetate. It features a cyclohexane ring with a methyl group (\( \text{CH}_3\)) attached at the second position. The acetate group, identified by the \( \text{OCOCH}_3 \) side chain, is also attached to the ring. The notation of "cis" indicates the arrangement of different groups on the same side of the cyclohexane ring.

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