Provide a 3-5 step synthetic route the target molecule from starting material A. Be sure to account for relative stereochemistry and to suggest reagents/conditions for each step CN CI H H3C CN Target molecule starting material (A)
Provide a 3-5 step synthetic route the target molecule from starting material A. Be sure to account for relative stereochemistry and to suggest reagents/conditions for each step CN CI H H3C CN Target molecule starting material (A)
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:**Title: Designing a Synthetic Route for a Target Molecule from Starting Material A**
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**Introduction:**
In this exercise, we explore a synthetic route to transform a given starting material into a target molecule. The process involves several chemical steps, where you must account for relative stereochemistry and suggest reagents and conditions used for each step.
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**Objective:**
- **Target Molecule:**
- Structure: A compound featuring an ester, nitrile, and aldehyde groups.
- Formula includes functional groups: CN (nitrile) and CO (ester and aldehyde).
- **Starting Material (A):**
- Structure: An alkene with a chloro substituent.
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**Instructions:**
1. **Identify Transformation Steps:**
- Convert the alkene to the desired functional groups.
- Replace the chlorine atom while ensuring the conservation of stereochemistry.
2. **Suggest Reagents/Conditions:**
- Consider reagents appropriate for:
- Halogen substitution.
- Alkene transformations.
- Addition of nitrile, ester, and aldehyde groups.
3. **Account for Stereochemistry:**
- Reflect stereochemical considerations in the proposed synthetic pathway.
4. **Plan a 3–5 Step Synthesis:**
- Ensure steps logically transform the starting material to the target.
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**Note:**
Developing a comprehensive synthetic route requires a detailed understanding of organic reactions and mechanisms. Each proposed step should be verified experimentally for efficiency and yield.
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