Provide a 3-5 step synthetic route the target molecule from starting material A. Be sure to account for relative stereochemistry and to suggest reagents/conditions for each step CN CI H H3C CN Target molecule starting material (A)

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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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**Title: Designing a Synthetic Route for a Target Molecule from Starting Material A**

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**Introduction:**

In this exercise, we explore a synthetic route to transform a given starting material into a target molecule. The process involves several chemical steps, where you must account for relative stereochemistry and suggest reagents and conditions used for each step. 

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**Objective:**

- **Target Molecule:**
  - Structure: A compound featuring an ester, nitrile, and aldehyde groups.
  - Formula includes functional groups: CN (nitrile) and CO (ester and aldehyde).

- **Starting Material (A):**
  - Structure: An alkene with a chloro substituent.

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**Instructions:**

1. **Identify Transformation Steps:**
   - Convert the alkene to the desired functional groups.
   - Replace the chlorine atom while ensuring the conservation of stereochemistry.

2. **Suggest Reagents/Conditions:**
   - Consider reagents appropriate for:
     - Halogen substitution.
     - Alkene transformations.
     - Addition of nitrile, ester, and aldehyde groups.

3. **Account for Stereochemistry:**
   - Reflect stereochemical considerations in the proposed synthetic pathway.

4. **Plan a 3–5 Step Synthesis:**
   - Ensure steps logically transform the starting material to the target.

---

**Note:**

Developing a comprehensive synthetic route requires a detailed understanding of organic reactions and mechanisms. Each proposed step should be verified experimentally for efficiency and yield.
Transcribed Image Text:**Title: Designing a Synthetic Route for a Target Molecule from Starting Material A** --- **Introduction:** In this exercise, we explore a synthetic route to transform a given starting material into a target molecule. The process involves several chemical steps, where you must account for relative stereochemistry and suggest reagents and conditions used for each step. --- **Objective:** - **Target Molecule:** - Structure: A compound featuring an ester, nitrile, and aldehyde groups. - Formula includes functional groups: CN (nitrile) and CO (ester and aldehyde). - **Starting Material (A):** - Structure: An alkene with a chloro substituent. --- **Instructions:** 1. **Identify Transformation Steps:** - Convert the alkene to the desired functional groups. - Replace the chlorine atom while ensuring the conservation of stereochemistry. 2. **Suggest Reagents/Conditions:** - Consider reagents appropriate for: - Halogen substitution. - Alkene transformations. - Addition of nitrile, ester, and aldehyde groups. 3. **Account for Stereochemistry:** - Reflect stereochemical considerations in the proposed synthetic pathway. 4. **Plan a 3–5 Step Synthesis:** - Ensure steps logically transform the starting material to the target. --- **Note:** Developing a comprehensive synthetic route requires a detailed understanding of organic reactions and mechanisms. Each proposed step should be verified experimentally for efficiency and yield.
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