1. Propose 3 separate retrosynthetic disconnection strategies, one to form bond a, one for bond b,and one for bond c.2. Provide the reactants needed to form the product given below. Draw the transition state forthis process. If attempted, this reaction would not actually work due to a very high AG. Explain why.[].3. Label all of the chemically distinct protons (a-z) and carbons (1-100) on each of the moleculesbelow. Predict the splitting patterns, integration, and relative chemical shifts for the protons and the relativechemical shifts for the carbons.4. Provide reagents and products after each step to complete the multi-step transformation below.Be careful of synthetic traps.OHOHOCH3OH

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1. Propose 3 separate retrosynthetic disconnection strategies, one to form bond a, one for bond b, and one for bond c

Chemistry

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

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Question

1. Propose 3 separate retrosynthetic disconnection strategies, one to form bond a, one for bond b,
and one for bond c.
2. Provide the reactants needed to form the product given below. Draw the transition state for
this process. If attempted, this reaction would not actually work due to a very high AG. Explain why.
[].
3. Label all of the chemically distinct protons (a-z) and carbons (1-100) on each of the molecules
below. Predict the splitting patterns, integration, and relative chemical shifts for the protons and the relative
chemical shifts for the carbons.
4. Provide reagents and products after each step to complete the multi-step transformation below.
Be careful of synthetic traps.
OH
OH
OCH3
OH

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