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1. Incontinentia pigmenti is an X-linked dominant disorder characterized by skin abnormalities that begin in childhood, usually a blistering rash which heals, followed by the development of harder skin growths. The skin may develop grey or brown patches which fade with time. Most XY and XX individuals affected with the disease do not survive to birth. Karla who XX has Incontinentia pigemnti, is planning on having children with Michael, who is XY and does not have this condition. What are the chances they will have a child with Incontinentia pigmenti? What is the sex chromosome composition of the affected children? Complete a Punnett square for this condition. Feel free to write out any explanation you might have as well.

1. Incontinentia pigmenti is an X-linked dominant disorder characterized by skin abnormalities that begin in childhood, usually a blistering rash which heals, followed by the development of harder skin growths. The skin may develop grey or brown patches which fade with time. Most XY and XX individuals affected with the disease do not survive to birth. Karla who XX has Incontinentia pigemnti, is planning on having children with Michael, who is XY and does not have this condition. What are the chances they will have a child with Incontinentia pigmenti? What is the sex chromosome composition of the affected children? Complete a Punnett square for this condition. Feel free to write out any explanation you might have as well.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Sex-linked practice problems 1. Incontinentia pigmenti is an X-linked dominant disorder characterized by skin abnormalities that begin in childhood, usually a blistering rash which heals, followed by the development of harder skin growths. The skin may develop grey or brown patches which fade with time. Most XY and XX individuals affected with the disease do not survive to birth. Karla who XX has Incontinentia pigemnti, is planning on having children with Michael, who is XY and does not have this condition. What are the chances they will have a child with Incontinentia pigmenti? What is the sex chromosome composition of the affected children? Complete a Punnett square for this condition. Feel free to write out any explanation you might have as well.
Transcribed Image Text:Sex-linked practice problems 1. Incontinentia pigmenti is an X-linked dominant disorder characterized by skin abnormalities that begin in childhood, usually a blistering rash which heals, followed by the development of harder skin growths. The skin may develop grey or brown patches which fade with time. Most XY and XX individuals affected with the disease do not survive to birth. Karla who XX has Incontinentia pigemnti, is planning on having children with Michael, who is XY and does not have this condition. What are the chances they will have a child with Incontinentia pigmenti? What is the sex chromosome composition of the affected children? Complete a Punnett square for this condition. Feel free to write out any explanation you might have as well.
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Incontinentia pigmenti (IP):

  • Incontinentia pigmenti (IP) is a genetic disorder that is inherited in X linked dominant pattern. The genes associated with these traits are located on the X chromosome. This disorder is characterized by skin abnormalities, blisters, and skin patches. 
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