1. Hypokalemia and hyperkalemia are conditions in which the plasma concentration of potassium is affected. The K+ concentration is low in hypokalemia and high in hyperkalemia. Calculate the resting membrane potential of neurons in normal conditions, during hypokalemia and hyperkalemia, consider the contribution of the Na*/K+ ATPase to calculate the Vm. Use the following values for different ionic concentrations in plasma and in the intracellular space Normal Hypokalemia Hyperkalemia [Na*]i [Na*]o [K*li [K*]o (mM) 15 15 15 (mM) 145 145 145 (mM) 150 150 150 (mM) 2.5 7 PNa 0.05 PK* 1.5 R = 8.314 J.K-1.mol-1 To convert temperatures from Celsius to Kelvin, add 273.15 F = 96485.309 amp.s.mol-1

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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1. Hypokalemia and hyperkalemia are conditions in which the plasma concentration
of potassium is affected. The K+ concentration is low in hypokalemia and high in
hyperkalemia.
Calculate the resting membrane potential of neurons in normal conditions, during
hypokalemia and hyperkalemia, consider the contribution of the Na+/K+ ATPase
to calculate the Vm.
Use the following values for different ionic concentrations in plasma and in the
intracellular space
Normal
Hypokalemia Hyperkalemia
[Na*]i
[Na*]o
[K*]i
[K*]o
PNa
PK*
(mM)
15
15
15
(mM)
145
145
145
(mM)
150
150
150
(mM)
2.5
7
+
0.05
r
1.5
R = 8.314 J.K-1.mol-1
To convert temperatures from Celsius to Kelvin, add 273.15
F = 96485.309 amp.s.mol-1
%3D
Transcribed Image Text:1. Hypokalemia and hyperkalemia are conditions in which the plasma concentration of potassium is affected. The K+ concentration is low in hypokalemia and high in hyperkalemia. Calculate the resting membrane potential of neurons in normal conditions, during hypokalemia and hyperkalemia, consider the contribution of the Na+/K+ ATPase to calculate the Vm. Use the following values for different ionic concentrations in plasma and in the intracellular space Normal Hypokalemia Hyperkalemia [Na*]i [Na*]o [K*]i [K*]o PNa PK* (mM) 15 15 15 (mM) 145 145 145 (mM) 150 150 150 (mM) 2.5 7 + 0.05 r 1.5 R = 8.314 J.K-1.mol-1 To convert temperatures from Celsius to Kelvin, add 273.15 F = 96485.309 amp.s.mol-1 %3D
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