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- 1. What is the active substance and activity/indication (e.g. antibacterial, anti-inflammatory) of sibuyas or Allium cepa?1. A macrolide containing a 15-membered lactone ring Erythromycin Telithromycin Clarithromycin Azithromycin 2. ALL are true about the activity of Macrolides EXCEPT: It is effective against syphilis infections it resembles that of penicillin it is very effective against G(-) bacteria it is effective against erysipelas infections 3. These are ALL causes of bacterial resistance against macrolides EXCEPT: active efflux bacterial endospores release of esterases modification of binding site 4. These are ALL adverse effects of Erythromycin EXCEPT: CYP450 inhibition Hepatotoxicity Neutropenia Acute cholestatic hepatitis 5. These are drugs that have prolonged half-life when taken with erythromycin EXCEPT: Rifampicin Lipitor Lanoxin Lasix12. Which of the following ligands cannot act as an ambidentate ligand? o nitrite, NO₂ ethylenediamine, NH₂CH₂CH₂NH₂ O thiosulfate, S₂032- O thiocyanate, SCN-
- 8) what as the reasons for me asuning a colored compound the absoobance of at 9ts À max9 the range of visible light a) A max b) Absoobance is moe accurate, Hhe determing sensitivity to distinguis h too in will be loweyt enor conco C) Better diff. conemical Compounds Better sensitiw'ty to distingueyb teoo d) Sturil ar conc. off Same chemical compoud.32) The below given characterization data belong the .. ? CacO.HO CaC,0,. H0 100C CaC0, + H0 1 a) X-ray Spectroscopy b) Infrared spectroscopy c) Atomic Force Microscopy d) Thermogravimetric Analysis Cac O 100'C CaCo. 840 C 226°C 346°C 980'C! 660 c Cao 420°C Temperature ("C) 33) Which one the below given responses are not among the Acute inflammation responses? a) Extensive collagen synthesis b) Phagocytosis c) Neovascularisation d) Framework Intact 34) Biomaterials surface coatings are applied to improve the implant integration to body. Sort the adherences of different coating techniques to surfaces from poor to good adherence and also according to thickness.Which of the following statements is true about macrolide antibiotics? Multiple Choice 1-They are considered bactericidal. 2-The most common adverse effect of these drugs is crystalluria. 3-They were discovered in 1935 as a by-product of the dye industry. 4-The newer derivatives include clarithromycin and dirithromycin.
- 9. A formula for an antifungal shampoo con- tains 2% w/v ketoconazole. How many grams of ketoconazole would be needed to prepare 25 liters of the shampoo? 9. 500 g ketoconazolei) Interpret safe human excreta disposal in the context of preventing the spread of infectious diseases.ii) What is the rigid dichotomy between grey water and black water?10. Patient was admitted to the hospital with complaints on malnutrition, light- colored feces, urine colored as «brown ale»; it was revealed icteric discolor of skin and sclera. Due to examination and laboratory serum tests, the doctor diagnoscd viral hepatitis. Why blood test is revealed the considerable increase of transaminase activity (ALT and AST) in this patient? For the answer: a) explain the reason for mentioned enzymes increascd activity in the blood; b) specify, what enzyme activity is increased in the largest degree in this pathology and why; 8.3. Ammonia Detoxification. Urea Cycle. Urea Cycle Disorders, Hyperammonemia 413 c) draw the graph indicating the change of these enzymes activity in this disorder; d) write down reactions catalyzed by these enzymes, give full names of direct and reversible reactions, specify coenzyme; e) point out thc Ritz ratio in this disorder.
- 1. Explain the theory of emulsion formation. 2. What is the difference between an oil-in-water and water-in-oil emulsion ? 3. What is the role of an emulsifying agent ? 4. how egg yolk acts as an emulsifying agent? cite references1. Discuss the three (3) possible ways by which microorganisms may utilize inorganic compounds. Anwer this comprehensively and discuss the three ways thoroughly.6. The physician ordered procarbazine HCl 100 mg/m² PO daily. The strength of the drug is 50 mg per capsule. How many capsules of this antineoplastic drug would you prepare for a child whose BSA is 0.51 m²?