1. a. Somtimes cyanides can by useful functional groups, but not in a way that we would typically think about them. Meo CN Promide a mechanism for the following transformations and provide the structure of A. LDA, THF, O C: NaH, THF, O C; then add then Br OMe Meo CN b. Sometimes Aldol-type products can be forged in non-canonical ways. Provide a mechanism for the following transformations. When necessary, depict all proton transfers. catalytic KCN он me H,O,, NaOH Ph THFM,0 Ph H. MEOH Ph OMe

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Chapter1: Chemical Foundations
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1. a. Somtimes cyanides can by useful functional groups, but not in a way that we would typically think about them.
Promide a mechanism for the following transformations and provide the structure of A.
LDA, THF, O *C:
NaH, THF, O "C;
A
then add
then
Br
OMe
Meo
CN
b. Sometimes Aldol-type products can be forged in non-canonical ways. Provide a mechanism for the following
transformations. When necessary, depict all proton transfors.
H,O, NaOH
catalytic
KCN
OH
Ph
THFH,O
Ph
Меон
Ph
OMe
Transcribed Image Text:1. a. Somtimes cyanides can by useful functional groups, but not in a way that we would typically think about them. Promide a mechanism for the following transformations and provide the structure of A. LDA, THF, O *C: NaH, THF, O "C; A then add then Br OMe Meo CN b. Sometimes Aldol-type products can be forged in non-canonical ways. Provide a mechanism for the following transformations. When necessary, depict all proton transfors. H,O, NaOH catalytic KCN OH Ph THFH,O Ph Меон Ph OMe
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