4. Reactivity. Propose a mechanism for each of the following transformations to explain the observed regioselectivity and stereochemistry. a. -COCI SiMe3 AICla CH2Cl2 Me Me 76%
4. Reactivity. Propose a mechanism for each of the following transformations to explain the observed regioselectivity and stereochemistry. a. -COCI SiMe3 AICla CH2Cl2 Me Me 76%
Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter19: Eas: Electrophilic Aromatic Substitution
Section: Chapter Questions
Problem 45E
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![4. Reactivity. Propose a mechanism for each of the following transformations to
explain the observed regioselectivity and stereochemistry.
a.
-COCI
SiMe3
AICI3
Mé
`Me
76%
b.
Me
(Ph;P)4Pd (cat.)
CO-Me
EtzN, CH3CN, reflux
Me
MeO2C
80%
с.
Me
Me
SiMe3
n-BugNF
DMF, HMPA
69%
d.
EtAICI (2 eq)
toluene
-SiMe3
85%](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F39285511-942f-4a28-a1ed-1df0a2f8d6cb%2F37632fe3-a98a-452d-af65-740b51563f0b%2Fspix6au_processed.png&w=3840&q=75)
Transcribed Image Text:4. Reactivity. Propose a mechanism for each of the following transformations to
explain the observed regioselectivity and stereochemistry.
a.
-COCI
SiMe3
AICI3
Mé
`Me
76%
b.
Me
(Ph;P)4Pd (cat.)
CO-Me
EtzN, CH3CN, reflux
Me
MeO2C
80%
с.
Me
Me
SiMe3
n-BugNF
DMF, HMPA
69%
d.
EtAICI (2 eq)
toluene
-SiMe3
85%
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