4. Reactivity. Propose a mechanism for each of the following transformations toexplain the observed regioselectivity and stereochemistry.a.-COCISiMe3AICI3Mé`Me76%b.Me(Ph;P)4Pd (cat.)CO-MeEtzN, CH3CN, refluxMeMeO2C80%с.MeMeSiMe3n-BugNFDMF, HMPA69%d.EtAICI (2 eq)toluene-SiMe385%

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4. Reactivity. Propose a mechanism for each of the following transformations to explain the observed regioselectivity and stereochemistry. a. -COCI SiMe3 AICla CH2Cl2 Me Me 76%

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Alkanes and Cycloalkanes

Alkanes are saturated organic compounds which are made up of C and H atoms. Alkanes have the general formula of CnH2n+2. Alkane contains sp3 hybridized carbon atoms with four sigmas (σ) bonds & every hydrogen atom is connected with one of the carbon atoms. The size of the alkane could be determined by the number of carbon atoms located in it.

Question

4. Reactivity. Propose a mechanism for each of the following transformations to
explain the observed regioselectivity and stereochemistry.
a.
-COCI
SiMe3
AICI3
Mé
`Me
76%
b.
Me
(Ph;P)4Pd (cat.)
CO-Me
EtzN, CH3CN, reflux
Me
MeO2C
80%
с.
Me
Me
SiMe3
n-BugNF
DMF, HMPA
69%
d.
EtAICI (2 eq)
toluene
-SiMe3
85%

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