b. Provide mechanisms and/or products for the following transformations. Pd°Ln, Cul, PhBr 1. HBpin, THF Et,N, THF H 2. Pd°Ln, PhBr, K3PO4, H2O/THF 3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide mechanisms for the reactions in the following sequence. Me Meo OMe MeN- MeN- N- MeN Br MeCN, 100 °C NaH, THF; Br H then 6M HCI MeO,C, -Me Me Meozc

b. Provide mechanisms and/or products for the following transformations. Pd°Ln, Cul, PhBr 1. HBpin, THF Et,N, THF H 2. Pd°Ln, PhBr, K3PO4, H2O/THF 3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide mechanisms for the reactions in the following sequence. Me Meo OMe MeN- MeN- N- MeN Br MeCN, 100 °C NaH, THF; Br H then 6M HCI MeO,C, -Me Me Meozc

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Galantamine, a natural product produced by the amaryllis family of flowering plants, has been used in the early treatment of Alzheimer's disease. In a synthesis of galantamine and related compounds (J. Org. Chem. 2015, 80, 1952-1956), compound 1 was converted into compound 2. Propose an efficient synthesis for the conversion of 1 to 2 A. NaOH MeO D. DMP or PCC G. HBr MeO B. H₂SO4, H₂O, HgSO4 E. Na2Cr₂O7, H₂SO4, H₂O H. 1) O3; 2) DMS H 2 The conversion of 1 to 2 can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order for each transformation, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. C. 1) BH3-THF; 2) H₂O2, NaOH F.HBr, ROOR I. TsCl, py Meo I₁, N Me Galanthamine OH
I'm having trouble understanding what's wrong with this mechanism I've drawn. Can you assist me in identifying the errors in the drawing? Thank you. Original Question: Propose a mechanism to show how 3,3-dimethylbut-1-ene reacts with dilute aqueous H2SO4H2SO4 to give 2,3-dimethylbutan-2-ol.
Give detailed Solution with explanation needed..please explain
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