1. A crossover study was conducted to investigate whether oat bran cereal helps to lower serum choles- terol levels in hypercholesterolemic males. Fourteen such individuals were randomly placed on a diet that included either oat bran or corn flakes; after two weeks, their low-density lipoprotein (LDL) cholesterol levels were recorded. Each man was then switched to the alternative diet. After a second two-week period, the LDL cholesterol level of each individual was again recorded. The data from this study are shown below. LDL (mmol/l) Subject Corn Flakes Oat Bran 1 4.61 3.84 2 6.42 5.57 3 5.40 5.85 4 4.54 4.80 5 3.98 3.68 6. 3.82 2.96 7 5.01 4.41 4.34 3.72 9. 3.80 3.49 10 4.56 3.84 11 5.35 5.26 12 3.89 3.73 13 2.25 1.84 14 4.24 4.14 (a) Which of the following data collection methods would be most appropriate in order to obtain data on subjects' cholesterol? (Provide a brief explanation) (i) Ask each subject what his/her cholesterol level is while on each diet. (ii) Have a medically trained professional do a standard laboratory cholesterol measurement for each subject while they are on each diet. (b) Are the two samples of data paired or independent?
1. A crossover study was conducted to investigate whether oat bran cereal helps to lower serum choles- terol levels in hypercholesterolemic males. Fourteen such individuals were randomly placed on a diet that included either oat bran or corn flakes; after two weeks, their low-density lipoprotein (LDL) cholesterol levels were recorded. Each man was then switched to the alternative diet. After a second two-week period, the LDL cholesterol level of each individual was again recorded. The data from this study are shown below. LDL (mmol/l) Subject Corn Flakes Oat Bran 1 4.61 3.84 2 6.42 5.57 3 5.40 5.85 4 4.54 4.80 5 3.98 3.68 6. 3.82 2.96 7 5.01 4.41 4.34 3.72 9. 3.80 3.49 10 4.56 3.84 11 5.35 5.26 12 3.89 3.73 13 2.25 1.84 14 4.24 4.14 (a) Which of the following data collection methods would be most appropriate in order to obtain data on subjects' cholesterol? (Provide a brief explanation) (i) Ask each subject what his/her cholesterol level is while on each diet. (ii) Have a medically trained professional do a standard laboratory cholesterol measurement for each subject while they are on each diet. (b) Are the two samples of data paired or independent?
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
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Transcribed Image Text:### Study Summary
A crossover study was conducted to examine the effects of oat bran cereal on serum cholesterol levels in males with hypercholesterolemia. Fourteen participants were assigned randomly to a diet including either oat bran or corn flakes. After two weeks, their low-density lipoprotein (LDL) cholesterol levels were measured. Each participant then switched to the alternate diet, and LDL levels were measured again after another two-week period.
#### LDL Cholesterol Levels (mmol/l)
| Subject | Corn Flakes | Oat Bran |
|---------|-------------|----------|
| 1 | 4.61 | 3.84 |
| 2 | 6.42 | 5.57 |
| 3 | 5.40 | 5.85 |
| 4 | 4.54 | 4.80 |
| 5 | 3.98 | 3.68 |
| 6 | 3.82 | 2.96 |
| 7 | 5.01 | 4.41 |
| 8 | 4.34 | 3.72 |
| 9 | 3.80 | 3.49 |
| 10 | 4.56 | 3.84 |
| 11 | 5.35 | 5.26 |
| 12 | 3.89 | 3.73 |
| 13 | 2.25 | 1.84 |
| 14 | 4.24 | 4.14 |
### Questions
**(a)** Which of the following data collection methods would be most appropriate to obtain data on subjects’ cholesterol?
- **(i)** Ask each subject what his/her cholesterol level is while on each diet.
- **(ii)** Have a medically trained professional conduct a standard laboratory cholesterol measurement for each subject while they are on each diet.
**Recommendation:** It is generally more reliable to have a medically trained professional measure cholesterol levels in a laboratory setting, as this ensures accurate and consistent data collection.
**(b)** Are the two samples of data paired or independent?
**Answer:** The samples are paired because each subject serves as their own control, experiencing both diets and providing related measurements under each condition.
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