### Concept Question**Question:**The three (3) component mixture of fluorenone, ferrocene, and 2-acetoxybenzoic acid (also known as aspirin) shown below was loaded on the column and eluted with 95:5 petroleum ether: diethyl ether. Using the **Molecular View of the column** provided: (a) Draw one (1) molecule of each analyte in the correct relative position in the column, and (b) Clearly show the relevant intermolecular forces that explain the column elution order. You do not need to include solvent molecules. (8 points)**Diagram Description:**1. **Simplified Column Diagram**: - The top and bottom of the column are indicated. - The structure of the column matrix is shown, which consists of recurring units of alumina (Al-OH groups) interacting through hydrogen bonding.2. **Molecular Structures**: - **Fluorenone**: A flat aromatic ketone structure with a carbonyl group (C=O) at its core. - **Ferrocene**: A metallocene with an iron (Fe) atom sandwiched between two cyclopentadienyl rings. - **2-Acetoxybenzoic acid (Aspirin)**: Consists of a benzene ring substituted with acetoxy (O–CO–CH3) and carboxylic acid (COOH) groups.**Instructions for Answer (for the student):**1. **Draw the Molecules**: - Place fluorenone, ferrocene, and aspirin at their respective positions within the column diagram. - Fluorenone, with its polar carbonyl group, will be positioned where interaction with the alumina via dipole-dipole forces is illustrated. - Ferrocene, nonpolar but with possible π-π interactions, will be shown at a higher position in the column due to less interaction. - Aspirin, with both hydrogen bonding (from –COOH group) and dipole interactions, would be shown interacting strongly at the mid-to-lower regions of the column.2. **Intermolecular Forces**: - **Fluorenone**: Highlight the dipole-dipole interaction between the carbonyl group (C=O) of fluorenone and the hydroxyl groups (Al-OH) on the alumina. - **

when two or more substances mix with each other without participating in a chemical change, the…

(1) The three (3) component mixture of fluorenone, ferrocene, and 2-acetyloxybenzoic acid (aka aspirin) shown below was loaded on the column and eluted with 95:5 petroleum ether: diethyl ether. Using the Molecular View of the column provided: (a) draw one (1) molecule of each analyte in the correct relative position in the column, and (b) clearly show the relevant intermolecular forces that explain the column elution order. You do not need to include solvent molecules. (8 points) buret wall AI top of column H Al- AI- H H IIIII -0-H -Ö-H bottom of column -‒‒‒‒‒‒‒. buret wall OH

(1) The three (3) component mixture of fluorenone, ferrocene, and 2-acetyloxybenzoic acid (aka aspirin) shown below was loaded on the column and eluted with 95:5 petroleum ether: diethyl ether. Using the Molecular View of the column provided: (a) draw one (1) molecule of each analyte in the correct relative position in the column, and (b) clearly show the relevant intermolecular forces that explain the column elution order. You do not need to include solvent molecules. (8 points) buret wall AI top of column H Al- AI- H H IIIII -0-H -Ö-H bottom of column -‒‒‒‒‒‒‒. buret wall OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

A 100 ml bottle of metronidazole 100 mg/ml suspension is available in your pharmacy. Calculate the volume of this suspension needed to be diluted with cherry syrup to prepare 60 ml of a 4% metronidazole suspension. 1 ml of a 1:1000 epinephrine injection was mixed with 20 ml of 1% lidocaine injection. Calculate the new ratio strength of epinephrine in the admixture. (IGNORE ANY VOLUME CHANGES AFTER ADMIXTURE) Instead of preparing 4 grams of tetracaine hydrochloride 4% gel an 8% gel was compounded by mistake. How many grams of the 8% gel and gel base must be mixed to get 4 grams of a 4% gel? How many milliliters of 70% ethanol and 20% ethanol must be mixed to prepare 500 ml of 30% ethanol? A diphenhydramine elixir contains 12.5 mg drug in one teaspoon. The volume of oral vehicle that is to be added to 100 ml of this elixir to reduce its strength by one half its original strength is; 6. 90 capsules of Liothyronine (T3) 15 micrograms are to be prepared. The formula calls for a 1:10000…
To separate three organic compounds from an aqueous solution, one basic, one acidic and one neutral apolar, by extraction technique, create an appropriate extraction scheme by writing examples for each and write down the reactions that took place at each stage.
Penicillin F is recovered from a dilute aqueous fermentation broth by extraction with amyl acetate, using 6.5 volumes of solvent per 100. volumes of the aqueous phase. At pH = 3.8 the distribution coefficient KD is 74. (a) What fraction of the penicillin would be recovered in a single ideal stage? (b) What would be the recovery with three-stage extraction using fresh solvent in both stages? (c) How many ideal stages would be needed to give the same recovery as in part (b) if a counterflow cascade were used with V/L = 0.065?
Florence is only able to find 0.015 M aqueous KI/I2 on the reagent cart, so they perform a dilution by combining 10 mL of water and 10 mL of the available reagent. They now have 0.0075 M aqueous KI/I2 which can be used at station C. Is there a difference in the chemical composition of the solution Florence made from what was available on the reagent cart? Group of answer choices no, because water was already present in the solution yes, because water was added to the solution
Caffeine Benzoic acid y = 66.391x R2E0.9995 y= 23.633x R? =0:9999 0.5 Injection Volume Injection Volume Aspartame Saccrine y = 6.2204x.. R2 =0.9997 y = 21.43x R² = 0.9891 2.5 0.5 2.5 Injection Volume Injection Volume (Abs) Peak height (Abs) Peak height 2. (Abs) Peak height (Abs) Peak height
The distribution constant for compound A between an organic solvent and water is 65. Calculate the concentration of compound A remaining in the aqueous layer after extraction of 50 mL of a 5 X 10-3 M aqueous solution of compound A with the following quantities of the organic solvent: (a) Two 25 mL portions (b) Four 12.5 mL portions
A sample may contain any combination of sodium hydroxide, sodium carbonate and sodium bicarbonate with inert matter. A 3.00g sample requires 57.57ml of 0.5N hydrochloric acid to reach phenolphthalein endpoint and a total of 105.4ml of acid was used until the methyl orange endpoint was reached. What is the percentage inerts in the mixture? What is the percentage sodium bicarbonate in the mixture? What is the percentage sodium hydroxide in the mixture? What is the percentage sodium carbonate in the mixture?
(2) Sally starts eluting her column with petroleum ether in hopes of separating her 50:50 ferrocene: fluorenone mixture. She notices her mobile phase getting low when there is limited separation between her two components. She eagerly adds more solvent to avoid her column from drying out. Sally then realizes she poured from her 1:1 petroleum ether: diethyl ether beaker rather than her petroleum ether beaker. (a) Using the molecular view below, explain how this would impact her product elution from the column. top of column H buret wall AI H H H H H H H H H H bottom of column buret wall (b) How does this error impact her experimental results? (c) Using pictures and words, how could Sally analyze the purity of her product? Fe
Tooth enamel consists mainly of the mineral calcium hydroxyapatite, Can(PO)(OH). Trace elements in teeth of archeological specimens provide anthropologists with clues about diet and disease of ancient people. Students at Hamline University measured the trace element strontium in cnamel from extract wisdom teeth by atomic absorption spectroscopy. Solutions were prepared with a constant total volume of 10.0mL. containing 0.750mg dissolved tooth enamel plus variable concentration of added Sr. \table[[Added Sr (ng/mL- ppb), Signal (arbitrary units)], [0, 28.0], [2.50, 34.3], [5.00, 42.8], [7.50, 51.5], [10.00, 58.6]] a) Prepare a graph to find the concentration of Sr in the 10mL sample solution in part per billion = n m L. (2%) b) Find the concentration of Sr in tooth enamel in part per million = μ (3%) 5. Tooth enamel consists mainly of the mineral calcium hydroxyapatite, Ca(PO)(OH). Trace elements in teeth of archeological specimens provide anthropologists with clues about diet and…
Predict three (3) correct apparatus used for the procedures experiment run by a chemist below. Determination of phosphorus in plant food will produced magnesium ammonium phosphate, MgNH4PO4.6H2O, precipitate. The precipitate was kept in a crucible and dry at 130 °C for 2 hours. Then, the precipitate was cooled for 15 minutes in a condition of low moisture atmosphere. The precipitate is weighed until constant weight is obtained.
The distribution ratio D for an analyte is defined as the ratio of its analytical concentration in two immiscible solvents (organic versus aqueous): D = Corg/Caq Show that the fraction of analyte remained in the aqueous phase after the extraction (from aqueous to organic) is given by the following: Fraction remained = Vaq/(VorgD + Vaq) where Vaq and Vorg are the volume of water and organic solvent used in the extraction, respectively.
The distribution constant for compound A between an organic solvent and water is 65. Calculate the concentration of compound A remaining in the aqueous layer after extraction of 50 mL of a 5 X 10-3 M aqueous solution of compound A with the following quantities of the organic solvent: (a) Two 25 mL portions (b) Four 12.5 mL portions