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- Which statement is INCORRECT? Select one: O A. The presence of oxygen and nitrogen containing functional groups in a drug usually enhances the lipophilicity OB. O C. The metabolism of drugs can involve demethylation and glucuronidation COX-1 & COX-2 are classified as NSAIDs OD. COX-1 and COX-2 synthesise inflammatory prostaglandins Course Hero 4 JD Course Hero 2 EPY C Please rat Q+ Exam.pdf - Study more efficiently and get your q. по N earn unlocks. 88 21°C ^ @ @ ↳ # X HOJ > 오후 10= 2023-06-Draw the organic product(s) for each of the following reactions. If there is more than one product likely indicate the major. Be sure and show any stereochemistry.6. Identifv each of the following reactions as an organic oxidation, reduction or neither. Pt + H, b. COO ÇO0 но -с — н C=0 Malate dehydrogenase CH; + NAD CH; + NADH + H COO COO Malate Oxaloacetate с. OH ACP + NADPH + H* ACP + NADP* d. OH + но
- provide brief explanation thnksWhich compound forms the higher concentration of hydrate at equilibrium, PhCOCHO or PhCH2CHO? Explain your reasoning.When the ammonium salt (CH3CH2CH2)3NHCl is treated with NaOH, the products are water, NaCl, and an organic product. Provide the product in an attached file.
- 2. Each of 10 stereoisomeric sugar derivatives can be prepared via a multiple-step synthesis starting from either glucuronolactone 1D or its enantiomer 1L. (J. Org. Chem. 2012, 77, 7777-7792). 1L A. Draw the structure of 1L. 1D OH HO N OH HO OH sugar derivative B. How many stereoisomers of 1D are possible? C. Now consider the 10 stereoisomeric sugar derivatives. Draw the structures of the eight chiral products (as pairs of enantiomers) and the two achiral products (hint: meso).A) The biotransformation of this drug: Choose all that apply. CH3 CH3 OH H,C он он HO H,C. Phase I Phase II Reductive reaction Oxidative reaction Hydrolysis reaction glucuronic acid conjugation sulfate conjugation O methylation O acetylation product becomes less water soluble Porducts become more water soluble excretion of the products mostly happens in kidney excretion of the product mostly happens in feces B) What is the enzyme and coenzyme/cosubsrate ?Give a concise svnthesis for the molecules if they start from a benzene. a. F- -Br b. Но. OH C.