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Helene Fuld College of Nursing *
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Medicine
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Jan 9, 2024
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docx
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Oral Glucose Tolerance Test (OGTT)
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Oral Glucose Tolerance Test (OGTT)
The OGTT's primary goal is to examine a person's capacity to manage blood glucose
levels. It is used to detect gestational diabetes mellitus (GDM), a type of diabetes that occurs
during pregnancy (Eyth et al., 2019). Fasting for at least 8 hours is required, followed by the
intake of a glucose-containing solution and numerous blood glucose tests (typically fasting, 1
hour, 2 hours, and 3 hours) to reveal aberrant glucose metabolism during pregnancy.
Target Group and Validation
The OGTT is designed exclusively for pregnant women to diagnose gestational diabetes.
It is not meant to be used in any other age group or situation. It has been evaluated and verified
in pregnant women to detect gestational diabetes (Héctor Gallardo-Rincón et al., 2022). Clinical
trials and research have shown its usefulness and reference values in this group.
Predictive Ability
The OGTT is considered a reliable and valid technique for detecting gestational diabetes.
It is the gold standard for this purpose, with well-established reference ranges and diagnostic
criteria. It delivers precise glucose readings at several time intervals, and high blood glucose
levels at any two or more of these intervals (fasting, 1 hour, 2 hours, or 3 hours) are suggestive of
gestational diabetes (Héctor Gallardo-Rincón et al., 2022). The predictive values are well-
documented, and the test is reliable in detecting GDM. The OGTT is susceptible to aberrant
glucose metabolism during pregnancy, particularly GDM. In research by Lapphart and
Liabsuetrakul (2020), the pooled sensitivity and specificity were 79% and 74%, respectively,
whereas sensitivity was more than 90% in others.
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OGT is a critical test that I would incorporate into my advanced practice. This test would
have been critical for my work with pregnant women, particularly those at risk of GDM, due to
its reliability, validity, and predictive characteristics, which make it a standard test for diagnosing
GDM.
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References
Eyth, E., Basit, H., & Smith, C. J. (2019, June).
Glucose tolerance test
. Nih.gov; StatPearls
Publishing. https://www.ncbi.nlm.nih.gov/books/NBK532915/
Héctor Gallardo-Rincón, Lomelín-Gascón, J., Luis Alberto Martínez-Juárez, Montoya, A.,
Janinne Ortega-Montiel, Galicia-Hernández, V., Diego-Abelardo Álvarez-Hernández,
Rosangela Ávila-Domínguez, Reyes-Muñoz, E., Lucía Marcela Illescas-Correa, Alberto,
D., Javier, F., Oswaldo, E., Alejandro Efraín Benitez-Herrera, Reyes-Gómez, D., María
Concepción Carmona-Ramos, Hernández-González, L., Romero-Islas, O., Mújica-
Rosales, R., & Tapia‐Conyer, R. (2022). Diagnostic Accuracy of Capillary Blood
Glucometer Testing for Gestational Diabetes.
Diabetes, Metabolic Syndrome and
Obesity: Targets and Therapy
,
Volume 15
, 3855–3870.
https://doi.org/10.2147/dmso.s389420
Lappharat, S., & Liabsuetrakul, T. (2020). Accuracy of screening tests for gestational diabetes
mellitus in Southeast Asia.
Medicine
,
99
(46), e23161.
https://doi.org/10.1097/md.0000000000023161