Ch12_CYU Questions_Daigle
docx
keyboard_arrow_up
School
Valencia College *
*We aren’t endorsed by this school
Course
2010C
Subject
Medicine
Date
Apr 3, 2024
Type
docx
Pages
3
Uploaded by bunnielover948
Origins of Antibiotics
What was the contribution of
Alexander Fleming
to antibiotic research?
What is the difference between an
antibiotic
, a
semisynthetic drug
,
and a
synthetic drug
?
What is a
prophylaxis
?
Spectrum of Antibiotic Activity
What is the difference between a
narrow-spectrum
and a
broad-
spectrum
drug?
Which type of drug is most desirable for use in the human host?
What complications can arise when broad-spectrum drugs are used for a long period of time?
Characteristics of An ideal Drug
What are some characteristics that clinicians look for in a chemotherapeutic agent?
Issues With Antibiotic Treatment
What three (3) factors should always be considered when determining the course of antibiotic treatment?
How might patient history be useful in determining whether or not to use a given antibiotic?
Mechanisms of Drug Action
What are the five (5) mechanisms of inhibition for chemotherapeutic agents?
Which mechanisms are the
least
harmful to the human host? Why?
Drugs That Inhibit Cell Walls
Why are
penicillin
and
cephalosporin
both effective inhibitors of peptidoglycan? What advantage does cephalosporin have over penicillin in the human host?
What is the most common use for
vancomycin
in the clinical setting?
Why is
isoniazid
considered one of the most narrow-spectrum drugs? What microbial infection is isoniazid useful against?
Drugs That Inhibit Protein Synthesis
Why are
tetracycline
,
streptomycin
, and
erythromycin
selectively toxic to bacteria and not humans?
Why is tetracycline rarely prescribed today, but erythromycin so commonly prescribed?
What one species produces over half of all the antibiotic currently used
today?
Drugs That Inhibit Folic Acid Synthesis
Why is
trimethoprim
selectively toxic to microbes despite the fact that we also need folic acid to make DNA and RNA nucleotides?
Why are trimethoprim and
sulfamethoxazole
often given together, rather than separately?
Drugs That Inhibit Cell Membranes (Lipids)
Why are
polymixins
selectively toxic to Gram-negative bacteria, and not Gram-positive?
Drugs That Affect Fungal Cell Membranes
Which drug is most commonly used to treat systemic fungal infections around the world?
Drugs That Affect Protozoans
What is the most common drug used world-wide for the treatment of malaria?
Why is the more effective
primaquine
not given instead?
Mechanisms of Drug Resistance
What are the five (5) most common mechanisms of drug resistance?
Human Role In Resistance
Why should antibiotics never be prescribed for most upper respiratory infections?
Why should patients always complete their entire course of antibiotics?
How can
probiotics
help before and after taking antibiotics?
Problems With Chemotherapeutic Agents
What are the three (3) most common problems seen in humans when using chemotherapeutic agents?
Why might a broad-spectrum antibiotic lead to a
superinfection
?
Your preview ends here
Eager to read complete document? Join bartleby learn and gain access to the full version
- Access to all documents
- Unlimited textbook solutions
- 24/7 expert homework help