Week 6 Experimental Studies Participation Activity
docx
keyboard_arrow_up
School
California State University, Fullerton *
*We aren’t endorsed by this school
Course
401
Subject
Medicine
Date
Dec 6, 2023
Type
docx
Pages
3
Uploaded by AmbassadorUniverse2702
Week 6 – Experimental Studies Participation Activity
For this activity, you may work individually or with one other classmate
. If you work with a
classmate, both names need to be on the submission or I can only give credit to the student who
submitted it. This is worth 18 participations points. It is due on Sunday, 10/1 @ 11:59pm PST.
Late submissions will be accepted up to 2 days after with a 10% penalty each day (ie. up to
20%).
Part I: Video (5 points)
Please watch the video titled “A History of Clinical Research” that was posted on the course
Canvas page. Based on the video, answer the following questions.
1. Discuss two specific historical examples of medicine or clinical research mentioned by Dr.
Gillings. (maximum 1-2 sentences for each) (2 points)
Edward Jenner conducted the renowned trial that demonstrated vaccination might prevent
smallpox in 1796. In 1754, surgeon James Lind meticulously examined several meals onboard
the HMS Salisbury, discovering that citrus fruit reduced scurvy and thereby saved lives.
2. According to Dr. Gillings, how many novel drug therapies has the FDA approved? (1 point)
1019 novel drugs therapies had been approved by the FDA.
3. Why do you think clinical trials are important when it comes to public health? Explain your
answer. (2 points)
Clinical trials are crucial in my opinion since they aid in the discovery of novel therapies for
diseases as well as methods to diagnose and minimize the risk of getting a condition.
Part II: Real-World Experimental Studies (13 points)
Please read the two real-world experimental study articles included on the course Canvas page.
Then, answer the following questions.
1. For each experimental study, what is the exposure? In other words, what were the researchers
testing on the participants? No explanations are needed. For example, if the study was testing the
effects of smoking on risk of getting lung cancer, the exposure would be smoking. (2 points)
Study #1 – Exposure: Cognitive exercises
Study #2 – Exposure: Aducanumab
2. For each experimental study, what is the outcome? In other words, what were the researchers
specifically evaluating as a result of giving the participants the exposure? No explanations are
needed. For example, if the study was testing the effects of smoking on risk of getting lung
cancer, the outcome would be lung cancer risk. (Note: This is NOT asking for the study’s results)
(2 points)
Study #1 – Outcome:
Boost protection against Dementia
Study #2 – Outcome: Reduce accumulation of amyloid plaque.
3. For each experimental study, briefly describe who was recruited. (1 point)
Study #1 – Recruited Population: 2,802 healthy seniors.
Study #2 – Recruited Population: Subjects suffering from memory and thinking problems or
diagnosed with early Alzheimer’s.
4. For each experimental study, list the specific exposure groups that were compared. For
example, if the study was testing the effects of smoking, the comparison groups may be smokers
and non-smokers. (2 points)
Study #1 – Exposure Comparison Groups: 2,802 healthy seniors divided into 3 groups; one
group classroom-based course designed to impart strategies aimed at boosting memory; a second
got a classroom-based course designed to sharpen participants' reasoning skills. A third group
was given computerized training.
Study #2 – Exposure Comparison Groups:
subjects suffering from memory and thinking
problems or diagnosed with early Alzheimer's given a medication named aducanumab compared
with subjects receiving a placebo medication.
5. For each experimental study, briefly describe what the researchers used to determine the
outcome being measured. For example, if the outcome was lung cancer risk, you should be
discussing how the researchers determined who had lung cancer and who didn’t. (2 points)
Study #1 – How the Outcome was Measured: participants' cognitive health was measured at one,
two, three, five and 10 years after initial training.
Study #2 – How the Outcome was Measured: using aducanumab therapy: higher doses
6. Which level of prevention best describes each experimental study? No explanations are
needed. (2 points)
Study #1 – Level of Prevention: Tertiary Prevention
Study #2 – Level of Prevention:
7. Even though you probably don’t qualify for either study, if you had to pick one study to
participate in, which would you choose and why? Think about the exposure, what’s required of
you as a participant as well as any other details you might consider before making such a
decision. Explain your answer. (2 points)
Your Choice: I'd like to take part in Study #1.
Explanation: I believe this would be the greatest option for me since I believe that in research #2,
if I am exposed to a placebo, I will have no idea what it is or how my body will react, which
could be bad. I would like study #1 since it would expose me to sessions that would assess my
cognitive health. I wouldn't have to be exposed to anything I don't already know about.. I
wouldn't need to be exposed to something I do not know about.
Your preview ends here
Eager to read complete document? Join bartleby learn and gain access to the full version
- Access to all documents
- Unlimited textbook solutions
- 24/7 expert homework help