Allergy & Immunology ____________________________________

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School

Georgia Piedmont Technical College *

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Course

2113

Subject

Medicine

Date

Dec 6, 2023

Type

pdf

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3

Uploaded by BarristerDugong2439

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Topic Search: Allergy & Immunology ____________________________________ Name: _Aden Gebregergs__________________________________________________ Date: _Nov/13/2023___________________ Period: __6th___________ Name of Article/Reading: ___Concept of 'Asthma-COPD Overlap' Still Alive Despite Detractors__ Author(s): __Nicole Lou_______________________________________________Review By: (Name of Physician)_____N.A_______________ 1. Reading and Understanding 2. Summarize the main points/facts in at least 6 paragraphs below: Paragraph #1:Dr Garbo Mak of UW Medicine argues for eliminating “ACO,” emphasizing the distinct risk factors, environmental exposures, and pathophysiology that distinguish asthma from COPD. Paragraph #2:Dr Nicola Hanania of Baylor College of Medicine has a contrary view, arguing that COA exists separately from asthma and COPD. It highlights common features with unique features, suggesting that COA may represent a spectrum between asthma and COPD. Paragraph #3:Proponents of COA propose that it represents a middle ground between asthma and COPD, in which individuals have many different characteristics. This group is often excluded from trials and the estimated incidence is 2-3% in the general population. Paragraph #4:Hanania focused on the medical way to treat ACO. He recommended using inhaled corticosteroids (ICS) first, instead of starting with long-acting beta-agonists (LABA) or long-acting muscarinic antagonists (LAMA) for COPD. He asked for long-term studies to learn about ACO's healthcare and how it naturally changes over time, and to create new ways to measure it.
Paragraph #5:The discussion addresses the complexity of asthma and COPD, emphasizing the importance of recognizing distinct entities for accurate diagnosis and treatment. The treatable trait model is discussed, focusing on individualized treatments for specific problems in each patient. 2. Write down any unfamiliar words or phrases Pathophysiologies, Phenotypes, Biomarkers, and Prognostic Implications 3. Look up the definition of at least one of the words from question 2. Pathophysiologies: The study of the disordered physiological processes associated with disease. 4. What is/are the main point(s) of the entire reading/article? The main point revolves around the ongoing debate among pulmonologists about classifying COA as a distinct respiratory disease. While some have argued for abandoning the term, citing differences in risk factors and pathophysiology between asthma and COPD, others argue that COA is a distinct entity with unique characteristics. unique point, potentially representing the spectrum between asthma and COPD. 5. Write down a minimum of 3 questions you still have after reading the article. (Use Level 1, 2, and 3 words) L1: What are the main arguments against recognizing ACO as a distinct airway disease?
L2: How does the prevalence of ACO vary in different populations, and why is it considered an understudied group? L3: What are the suggested strategies for managing patients with ACO, and how do they differ from traditional approaches for asthma and COPD?
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