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Walden University *
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Medicine
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Nov 24, 2024
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pptx
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Aspirin as an Efficacious Prophylaxis for Preventing Deep Vein Thrombosis (DVT) after Orthopedic Surgery: An Evidence-Based Practice Project
Nicole Rengifo
Fairleigh Dickinson University, Teaneck, NJ 07666
Abstract
Deep vein thrombosis (DVT) and
Pulmonary Embolism (PE) are
severe complications of orthopedic
surgery
It is imperative to develop evidence-
based practice (EBP) guidelines to
reduce the risk
Statement of the EBP Problem
There is lack of consensus regarding
the most efficacious prophylactic
agent for Deep Vein Thrombosis
The regional hospital also lacks a
uniform policy on the use of
prophylactic regimens for preventing
DVT
Purpose Statement
The purpose of this review is to
develop a standardized evidence-based
protocol that recommends aspirin as the
first-line DVT prophylaxis
PICO Question
In the adult population undergoing
elective joint replacement surgery
(P)
,
is Aspirin
(I)
compared to Coumadin
(C)
more efficacious in preventing
deep vein thrombosis and bleeding
(O)
3-5 days postoperatively
(T)
?
Implementation Model
The IOWA model will guide the
implementation process by
emphasizing organization and
collaboration in conducting and
using research
Integration of Evidence
The regional orthopedic hospital is
developing a clinical improvement
project
The QI proposal acknowledges the
clinical implications of venous
thromboembolism (VTE)
Administrators and clinicians have
endorsed the need for a standardized
prophylaxis protocol for VTE
EBP Setting
A 24-bed orthopedic unit of a regional
hospital in New Jersey
Implementation Procedures
Formation of an implementation team
consisting of all stakeholders
Bottom-up and participatory approach
to decision-making process and
implementation
Facilitating Factors
Organizational support, teamwork and
effectual communication
Barriers to Implementation
Resistance to change, limited
knowledge, and paper-based systems
Data Collection/Management
Data collection form and interviews
with stakeholders
Quality Improvement (QI) team to
manage the data
Data Analysis/Interpretation
•
Analysis of data using descriptive
and inferential statistics
•
Interpretation of data using
performance and outcome
benchmarks
Summary
Standardized approach to DVT
prophylaxis
Periodic assessment to support
continuous quality improvement
References
Becattini, C. et al. (2012). Aspirin for the prevention
of recurrence of venous thromboembolism.
New
England Journal of Medicine, 366
(21), 1959-1967.
Bozic, K. J. et al.
(2010). Does aspirin have a role in
venous thromboembolism prophylaxis in total knee
arthroplasty patients?
Journal of Arthroplasty, 25
(7),
1053–1060.
Simes, J. et al.
(2014). Aspirin for the prevention of
recurrent venous thromboembolism: The INSPIRE
collaboration.
Circulation, 130,
1062-1071.
Woller, S. C. et al. (2012). A prospective comparison
of warfarin to aspirin for thromboprophylaxis in total
hip and total knee arthroplasty.
The Journal of
Arthroplasty, 27
(1), 1–9.
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