PhysioEx Exercise 1 Activity 4
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PhysioEx Lab Report
Exercise 1: Cell Transport Mechanisms and Permeability
Activity 4: Simulating Filtration
Name: Jackie Chau
Date: 14 September 2023
Session ID: session-90d13d2b-01b7-eaf1-f72e-38373976f877
Pre-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
Experiment Results
Predict Questions
Filtration is a process that
You correctly answered:
is passive.
1
Filtration is dependent upon a
You correctly answered:
hydrostatic pressure gradient.
2
The
fi
ltrate
You correctly answered:
All of these answers are correct.
3
An important place that
fi
ltration takes place in the body is in
You correctly answered:
the kidneys.
4
Predict Question 1: What e
ff
ect will increasing the pore size of the
fi
lter have on the
fi
ltration rate?
Your answer:
The
fi
ltration rate will increase.
1
Predict Question 2: What will happen if you increase the pressure above the beaker
(the driving pressure)?
Your answer:
The
fi
ltration rate will increase.
2
Stop & Think Questions
Experiment Data
Run
Number
Solute
MWCO
Pressure
(mm Hg)
Filter
Rate
(ml/sec)
Residue
Start
Conc.
(mg/ml)
Filter
Conc.
(mg/ml)
1
Na
Cl
20
50
1.00
present
5
0.00
1
Urea
20
50
1.00
present
5
0.00
1
Glucose
20
50
1.00
present
5
0.00
1
Powdered
Charcoal
20
50
1.00
present
5
0.00
2
Na
Cl
50
50
2.50
present
5
4.81
2
Urea
50
50
2.50
present
5
0.00
2
Glucose
50
50
2.50
present
5
0.00
2
Powdered
Charcoal
50
50
2.50
present
5
0.00
3
Na
Cl
200
50
10.00
present
5
4.81
3
Urea
200
50
10.00
present
5
4.74
3
Glucose
200
50
10.00
present
5
4.39
3
Powdered
Charcoal
200
50
10.00
present
5
0.00
4
Na
Cl
200
100
20.00
present
5
4.81
4
Urea
200
100
20.00
present
5
4.74
4
Glucose
200
100
20.00
present
5
4.39
4
Powdered
Charcoal
200
100
20.00
present
5
0.00
Post-lab Quiz Results
The reason none of the solutes were present in the
fi
ltrate was that
You correctly answered:
the solutes were all too large to pass through.
1
What does an increase in the driving pressure correspond to in the body?
You correctly answered:
an increase in blood pressure.
2
+
-
+
-
+
-
+
-
You scored 100% by answering 4 out of 4 questions correctly.
Review Sheet Results
After
fi
ltration, substances that pass through the
fi
lter are called the
fi
ltrate, which
includes
You correctly answered:
all of the above.
1
The top beaker in the simulation corresponds to
You correctly answered:
the blood capillary.
2
Why was there not 100% recovery of the Na
Cl solute with any of the membranes?
You correctly answered:
Some of the solute remained on the membrane
fi
lter.
3
+
-
An increase in blood pressure would probably initially __________
fi
ltration in the
kidneys.
You correctly answered:
increase the rate of.
4
Explain in your own words why increasing the pore size increased the
fi
ltration rate.
Use an analogy to support your statement. How well did the results compare with
your prediction?
Your answer:
Increasing the pore size of the
fi
lter increases the
fi
ltration rate because it will allow
more solutes and solvent to pass through to the other side of the membrane. It is
very similar to if you were trying to let 10 people through a big car garage door
where all of them can enter all at once to get into the house while the front door
would only let only one person in at a time.
1
Which solute did not appear in the
fi
ltrate using any of the membranes? Explain
why.
Your answer:
One solute that did not appear in the
fi
ltrate was the powdered charcoal. I think it
did not appear in any of the membranes because it is much larger than any of the
2
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membrane pores used in the experiment. Therefore it would not have been able to
pass through to be a part of the
fi
ltrate past the
fi
lter.
Why did increasing the pressure increase the
fi
ltration rate but not the
concentration of solutes? How well did the results compare with your prediction?
Your answer:
The reason why increasing the pressure will increase the rate of
fi
ltration but not
the concentration of solutes is because you are pretty much just pushing the
solvent through the
fi
lter to
fi
lter at a faster rate but you can not alter the size of the
solutes being
fi
ltered out unless you want to modify the structures of it. For
example, the powdered charcoal was always
fi
ltered out of the
fi
ltrate for all parts
of the experiment no matter how much pressure was applied, because it was just
too big than the available pores in the experiment, it was always
fi
ltered out no
matter what.
3
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