201_F23_acid_base_reflection_draft_1

In this lab you are performing your first organic synthesis and safety information on all the materials you are using must be obtained. Companies are required to provide material safety data sheets (MSDS) for chemical compounds they sell. Please examine the MSDS for salicylic acid, available here. You will find GHS pictograms within the sheet that summarize the main hazards of this compound. The pictograms are essentially the same as the symbols on WHMIS labels, available here for reference. Based on the pictograms, whatare the main hazards for salicylic acid? Select as many answers as appropriate Select one or more: Acute oral or inhalation toxicity Flammable material Carcinogen Self-reactive substance Gas under pressure Corrosive Oxidizing material

In this lab you are performing your first organic synthesis and safety information on all the materials you are using must be obtained. Companies are required to provide material safety data sheets (MSDS) for chemical compounds they sell. Please examine the MSDS for acetic anhydride, available here. You will find GHS pictograms within the sheet that summarize the main hazards of this compound. The pictograms are essentially the same as the symbols on WHMIS labels, available here for reference. Based on the pictograms, whatare the main hazards for acetic anhydride? Select as many answers as appropriate Select one or more: Carcinogen Gas under pressure Acute oral or inhalation toxicity Corrosive Flammable material Oxidizing material Self-reactive substance

Answer the following questions following a Solubility and recrystalization lab for organic chemisty.  1. In a solubility and recrystallization lab you are working with the following chemicals : solids (benzoic acid, acetanilide,naphthalene, and resorcinol) and three solvents (water, ethanol and petroleumether) discuss and rank the polarity of the solvents and the polarity of the compounds being investigated. 2. Briefly describe how a mixture of sand and benzoic acid (soluble in hotwater) could be separated to produce pure benzoic acid.

You are employed as a coop student at the Drug and Alcohol Testing Association of Canada (DATAC) developing analytical tests for sports doping agents. You are asked to prepare a procedure for the extraction of methylphenidate, the active compound in Ritalin, from urine samples (consider them as simple aqueous layers, you do not need to consider other components!). The goal of the procedure is to extract the methylphenidate into an organic layer which will then be evaporated, and the residue will be tested for the drug.You find that methylphenidate is highly soluble in 2-methyltetrahydrofuran, a bio-renewable solvent. Draw the structure of 2-methyltetrahydrofuran and give two reasons why it is a good solvent choice for liquid-liquid extraction.

The Background section of this lab explains why weight percent (%w/w) can be useful for comparing the relative amount of a desired or "active" compound in different products. During the lab, a major goal will be to decide which of your experiment flasks yield data that would allow you to correctly calculate the %w/w of sodium bicarbonate in these tablets. Let's assume that you correctly choose one flask for this calculation. If the amount of NaHCO3 in that flask was 2.80 g and the original weight of the tablet was 4.50 g, what is the %w/w NaHCO3 in the tablet that went into this flask? GIVE YOUR ANSWER TO TWO DECIMAL PLACES. Your Answer: Answer

You are asked by your chemistry teacher to find: a) the solubility of different carboxylic acids in water and b) whether there is a connection between solubility and structure of different carboxylic acids. Follow the questions below to design and conduct an experiment to determine an answer to this question. a. From the paragraph above, write a question out that you will try and answer from conducting an experiment (C:2) b. Based upon your knowledge of the physical properties of organic compounds, hypothesize an order of solubility from lowest to highest: (1:3) Organic Compound Order of solubility (1=lowest, 3=highest) Pentanoic acid Hexanoic acid Ethanoic acid c. Provide an overall explanation for your hypothesis based upon your knowledge of physical properties. (A:3) d. Based upon the materials listed below, design a step by step experiment to test your hypothesis. Provide your individual steps. Include all the materials listed below. (1:3) Materials: CH,(CH,4COOH (), CH,COOH (),…

Fix each molecule in the drawing area below so that it has the structure it would have if it were dissolved in a 0.1 (aq) solution of NaOH 3-hydroxypropanoic acid and 1,3-dihydroxy-2-propanone .

A student use the same protocol as in the lab manual to extract benzoic acid, phenol, and naphthalene. Below are the steps he took Step 1 - Dissolve all three in 15 ml ether and place in separatory funnel Step 2- Add 15 ml of sodium carbonate and mix well Step3 - Isolate the aqueous layer and Add hydrochloric acid, which resulted in a precipitate Step 4- Add 15 ml of sodium hydroxide to the ether layer and mix Step 5- Isolate the aqueous layer and add hydrochloric acid, which resulted in a precipitate. Step 6- dry the ether layer and collect the solid that is left

Table 1 lists 33 pure compounds, several of which you will select to mix with each of your unknowns, so that you can determine the melting points of the mixtures, and thus the identity of the unknowns.   Table 1.  Known Compounds for Melting Point Experiment     COMPOUND mp range (oC)   COMPOUND mp range (oC)   1)   1,4-dimethoxybenzene   54-56        21)   4-nitroaniline   146-149   2)   2-phenylphenol   57-59        22)   1-napthoic acid   158-160   3)   diphenylacetylene   59-61        23)   salicylic acid   159-161   4)   2,4,6-trichlorophenol   64-66        24)   triphenylmethanol   160-162   5)   biphenyl   68-70        25)   sulfanilamide   165-167   6)   methyl 3-nitrobenzoate   78-80        26)   4-bromoacetanilide   165-169   7)   naphthalene   80-82        27)   itaconic acid   165-168   8)   vanillin   81-83        28)   d-mannitol   166-168   9)…

Estrogens are female sex hormones, the most potent of which is B-estradiol. OH AYA Но B-Estradiol In recent years, chemists have focused on designing and synthesizing molecules that bind to estrogen receptors. One target of this research has been nonsteroidal estrogen antagonists, compounds that interact with estrogen receptors and block the effects of both endogenous and exogenous estrogens. A feature common to one type of nonste- roidal estrogen antagonist is the presence of a 1,2-diphenylethylene with one of the benzene rings bearing a dialkylaminoethoxyl substituent. The first nonsteroidal estrogen antagonist of this type to achieve clinical importance was tamoxifen, now an important drug in the treatment of breast cancer. Tamoxifen has the Z configuration shown here. NMeg A B NMeg ? ОН Tamoxifen Propose reagents for the conversion of A to tamoxifen. Note: The final step in this synthesis gives a mixture of E and Z isomers.

Your employer hands you a heterogeneous mixture and asks you to isolate all of thehexane that you can from it. After some analysis, you determine that the mixture contains toluene, hexane,benzoic acid, water, sodium chloride, and sand. Explain how you would isolate pure hexane from thismixture. Remember that you can use techniques such as filtration, extractions, and acid/base chemistrythat we learned earlier in this course in addition to distillation. You may need to look up solubilities and/orboiling points online to solve this problem. You only need to isolate the hexane?

Dr. Frank's Magical Cure-all Cough Syrup contains three ingredients, shown below. You seek to isolate these three ingredients to further quantify and analyze them, something that can be achieved via liquid-liquid extraction. Propose a flow chart demonstrating how you would separate each of the components into a distinct organic layer. This flowchart should represent all of the chemicals required for the separation, and depict accurate representations of the chemical species throughout the process. H H. НО

Can you please fill the rest of this chart

Fischer Ester Synthesis Experiment: What does a refractive index of 1.38 (literature value = 1.40) tell you about the target compunds identity and purity? Essentially what can we infer about our results if our refractive index is 1.38 in regards to the Fischer Ester Synthesis Experiment.

(neutralisation reaction) use the given guidelines to solve this question

Question 1 You are employed as a co-op student at the Drug and Alcohol Testing Association of Canada (DATAC) developing analytical tests for sports doping agents. You are asked to prepare a procedure for the extraction of methylphenidate, the active compound in Ritalin, from urine samples (consider them as simple aqueous layers, you do not need to consider other components!). The goal of the procedure is to extract the methylphenidate into an organic layer which will then be evaporated and the residue will be tested for the drug. You find that methylphenidate is highly soluble in 2-methyltetrahydrofuran, a bio-renewable solvent. Draw the structure of 2-methyltetrahydrofuran and give two reasons why it is a good solvent choice for liquid-liquid extraction. (Please find the image attached below to help you with this question) Question 2 (cont. from scenario 1). Your colleague is helping you develop the urine test. They suggest that the urine should be adjusted to a pH above 7 before…

Select your two favorite amino acids. Draw them with correct stereochemistry and embed a picture of your drawings in your response. Then discuss: If these two molecules encountered each other in aqueous solution, what intermolecular interactions could be observed between the two molecules? How would changing the pH of the solution affect these interactions between the amino acids?