Exam 3 Practice Exam

Answer the following question below for the reaction of (R)-1-bromo-1-phenylethane with sodium azide in a water/ethanol solution. a) Kinetics experiments have determined that the reaction is only dependent on the concentration of 1-bromo-1-phenylethane. Is this an SN1 or SN2 mechanism? b) Draw an energy diagram for the reaction. Label all parts. Assume that the products are lower in energy than the reactants.

Zaitsev's rules predicts generally formed preferentially by both E1 and E2 mechanisms. A) more substituted alkenes B) less substituted alkenes C) tertiary alkyl halides D) primary alkyl halides are

please answer in text form and in proper format answer with must explanation , calculation for each part and steps clearly

Rank the following groups in order of their ability to activate an aromatic compound to electrophilic aromatic substitution.

Draw a mechanism and energy profile diagram when propane reacts with Bromine. Indicate minor and major products. Which product is more stable and why? What is Hammond's postulate?

Can you explain it? Provide examples with the various steps and explanations. How halogens affect the boiling/melting point? Does number of halogens affect it? For example, Ch3-Ch3 vs Ch3-Br vs Br-Ch3-Br

[Review Topics] [References] Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. %3D H3C CH3 HO-CH3 • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. • Do not include counter-ions, e.g., Na*, I', in your answer. • In cases where there is more than one answer, just draw one. C P. opy Bste C. Previous Next Email Instructor Save and Exit Cengage Learning | Cengage Technical Support 5:50 PM arch 82°F 3/28/2022

Which of these statements is correct? A) Sn1 and Sn2 reactions create and break a bondto carbonB) Sn2 and E2 reactions create a carbon-carbondouble bondC) Sn2 and E2 reactions must have a Lewis baseD) The alkene in electrophilic additions of alkenesis the electrophileE) None of the above statements is correct

Possible alternative brominations include: Veratrole (1,2-dimethoxybenzene) to 1,2-dibromo-4,5-dimethoxybenzene; 4-Methylacetanilide to 2-bromo-4-methylacetanilide; 2-Methylacetanilide (made in experiment S.1) to 4-bromo-2-methylacetanilide; Vanillin to 5-bromovanillin; Acetanilide to 4-bromoacetanilide; a. b. C. d. e. EXPERIMENT S4: BROMINATION OF AROMATIC COMPOUNDS Certain other acetanilides made in experiment S.1 may also be used as precursors in this experiment. Estimated time: 1 afternoon Associated learning goals: Section 6, LG 6.6; Section 7, LG 7.2 and 7.4 Pre-lab report: complete the standard report form, and answer the following questions. In this experiment, molecular bromine (Br2) is generated from the redox reaction of potassium bromate with hydrobromic acid. Write a balanced equation for this process. Briefly outline the mechanism by which Br2 brominates your aromatic compound. Why do the bromine atoms end up at the positions indicated rather than anywhere else in the…

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Draw the products resulting from addition of a Grignard reagent to an aldehyde. Use a dash or wedge bond to indicate stereochemistry of substituents on asymmetric centers, Ignore any inorganic byproducts. 1) PhMgCl (C6H5MgCl) 2) HCI/H₂O Type here to search H

What alkene is needed to synthesize the following 1,2-diol using the given reagents? Be sure to answer all parts. CH3CH₂CH2 [1] OsO4 followed by NaHSO3 in H₂O: [2] CH3CO3H followed by "OH in H₂O: H OH OH CH₂CH₂CH3 draw structure... draw structure ...

Curved arrows are used to illustrate the flow of electrons. Using the provided starting and product structures, draw the curved electron-pushing arrows for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bond-making steps. 1 I I :O: H Select to Add Arrows ether EN: CH2N2 :O: NEN: Problem 13 of 20 Please select a drawing or reagent from the question area Submit

Draw a structural formula(s) for the major organic product(s) of the following reaction. Br formic acid + НСОН CH3CHCH2CH2CH3 Renantiomer • Use the wedge/hash bond tools to indicate stereochemistry where it exists. • You do not have to explicitly draw H atoms. • If a group is achiral, do not use wedged or hashed bonds on it. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple products using the + sign from the drop-down menu.

A benzene ring alters the reactivity of a neighboring group in the so-called “benzylic” position, similarly to how a double bond alters the reactivity of groups in the “allylic” position. Benzylic cations, anions, and radicals are all more stable than simple alkyl intermediates. a) Use resonance structures to show the delocalization of the positive charge, negative charge, and unpaired electron of the benzyl cation, anion, and radical.

What is the mechanism to get from the reactant to the products

9) Suppose I want to perform a simple substitution reaction, replacing the OH with a Cl in the following compound. Which of the following reagents works best? Explain (and that means explain why the wrong answers are wrong as well as why the right answer is right). Option A: Addition of HBr Option B: Addition of SOC12/pyridine Option C: Addition of SOCl2 only OH ? J1

Draw the four resonance structures formed during bromination of methoxybenzene, CH3OC6H5, with Br2/FeBr3 to give para-bromomethoxybenzene and then circle the most stable resonance form.

Rank the compounds according to their increasing reactivity toward electrophilic substitution. 1. Benzaldehyde 2. o-dimethylbenzene 3. nitrobenzene 4. phenol

Draw the major organic product(s) of the following reactions including stereochemistry when it is appropriate. CH3CH2-CEC-CH3 H₂O/H2SO4/HgSO4 • • • Use the wedge/hash bond tools to indicate stereochemistry where it exists. If no reaction occurs, draw the organic starting material. Separate multiple products using the + sign from the drop-down menu. 2624 ChemDes ? T

Alkyl halides 1-chlorobutane 2-chlorobutane Allyl chloride 2-chloro-2-methylpropane 1-chloro-2-methylpropane 2-bromobutane SN1 conditions = Silver Nitrate in Ethanol 1. Rank the alkyl halides according to their SN1 reactivity. If compounds are similar in reactivity, you may group them in your ranking. Considering substitution, leaving group, temperature, solvent, etc... provide an explanation for each pairwise ranking.

Electrophilic aromatic substitutions proceed in two stages. 1. Attack of the aromatic ring on the electrophile. 2. Regeneration of the stable aromatic system by loss of a positively charged unit, usually a proton. Br Br₂/FeBr3 Draw one resonance structure for the intermediate formed when the electrophile is attacked by benzene in the reaction above. • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading.