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Chamberlain University College of Nursing *

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6373

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Chemistry

Date

Nov 24, 2024

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pdf

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1

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What PIAs are methyl isopropyl ethers? methyl ethyl ethers? - ANSWER- methyl isopropyl ether = sevoflurane methyl ethyl ether = isoflurane and desflurane What PIA is not metabolized to TFA? - ANSWER- Sevoflurane not metabolized to TFA, but is broken down to inorganic fluoride ions What local anesthetics can cause methemoglobinemia? - ANSWER- benzocaine, cetacaine (contains benzocaine), prilocaine, EMLA cream (contains prilocaine) What are the three components of a local anesthetic molecule? - ANSWER- benzene ring, intermediate chain (ester vs amide), tertiary amine What local anesthetic is metabolized to O-toluidine? - ANSWER- prilocaine Maximum dose of cocaine when used as a local anesthetic in adults - ANSWER- 150-200 mg What subunits must be occupied to open the nicotinic receptor at the motor end plate? - ANSWER- two alpha subunits What are the five subunits on the nicotinic receptor? - ANSWER- 2 alpha, 1 beta, 1 delta, 1 epsilon What are the two pathological variants of the nicotinic receptor? - ANSWER- 1) episilon replaced by gamma subunit
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