BROOKER BIOLOGY
5th Edition
ISBN: 9781307656152
Author: BROOKER
Publisher: MCG/CREATE
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Chapter 9.5, Problem 2EQ
Summary Introduction
To determine: Whether prednisolone inhibits the ability of rats to make their own ACTH when they were injected with both prednisolone and ACTH.
Introduction: In the process of apoptosis, first the cell shrinks and the destruction of internal structures like nucleus and cytoskeleton begins which results in the cell to become round shaped. Then plasma membrane forms irregular extensions which result in breaking as small fragments
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Overexpression of this receptor in the cells of the adrenal gland causes Cushing's syndrome, a disease caused
by the overproduction of cortisol. One strategy that scientists have employed to treat this disease is the use of
small molecules that bind to, but do not activate, MC2R. This type of molecule is generically referred to as an
antagonist. How can an antagonist bind to the same receptor as ACTH but not activate it?
O a. The antagonist can bind covalently while ACTH binds non-covalently
O b. The antagonist is only partially complimentary to the binding pocket of MC2R
O The antagonist binds to ACTH and blocks it from binding to the receptor properly
O d. The antagonist is the exact same structure as ACTH but since it is synthetic it doesn't work
One cause of Cushing's syndrome is the inappropriate production of GPCRS in the adrenal gland that are not
normally present in those cells. When these receptors are activated they result in the production of cortisol.
Which statement about…
What is the effect of marijuana in animals?
Long-term methamphetamine use leads to changes in the brain. Think about how methamphetamine changed where dopamine was found in the cell. What are some changes that you might expect based on this simulation?
Chapter 9 Solutions
BROOKER BIOLOGY
Ch. 9.1 - Figure 9.1 Response of a yeast cell to glucose....Ch. 9.1 - Prob. 1CSCh. 9.1 - Which type of signal, paracrine or endocrine, is...Ch. 9.1 - Prob. 3CCCh. 9.2 - Prob. 1CSCh. 9.2 - Prob. 2CSCh. 9.2 - Prob. 1CCCh. 9.3 - Prob. 1CSCh. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CC
Ch. 9.3 - In the case of signaling pathways involving...Ch. 9.5 - Prob. 1EQCh. 9.5 - Prob. 2EQCh. 9.5 - Prob. 3EQCh. 9.5 - Prob. 1CCCh. 9 - Prob. 1TYCh. 9 - Prob. 2TYCh. 9 - Prob. 3TYCh. 9 - Prob. 4TYCh. 9 - Prob. 5TYCh. 9 - The relay protein Ras is part of the EGF pathway...Ch. 9 - Prob. 7TYCh. 9 - Prob. 8TYCh. 9 - Prob. 9TYCh. 9 - Prob. 10TYCh. 9 - Prob. 1CQCh. 9 - Conceptual Questions What are the three stages of...Ch. 9 - Prob. 3CQCh. 9 - Prob. 1COQCh. 9 - Prob. 2COQ
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