EBK HUMAN ANAT.+PHYSIOLOGY
11th Edition
ISBN: 9780134807362
Author: Marieb
Publisher: PEARSON CO
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Textbook Question
Chapter 9, Problem 2CCS
Children with Muscular Disorders
You're doing a clinical rotation with Dr. Barr, a world-renowned specialist in children's muscle disorders. On your first day, you meet three patients with the same probable diagnosis—nemaline myopathy. Jodi, age 2, has a waddling walk and difficulty standing; Linda. 6 months, has pneumonia associated with problems swallowing; and Tom, 12, has progressive weakness with foot drop and difficulty walking.
“This kind of variation is not surprising.” says Dr. Barr. “A mutation in one of 11 different genes related to thin filaments can cause nemaline myopathy, so you’d expect to see it present in different ways.”
Dr. Barr has scheduled all three children for a muscle biopsy (surgical removal of a small piece of muscle tissue for examination). He explains to you. “We’re going to use these biopsies for two things. First, we're going to look for the characteristic histology of nemaline myopathy. Second, we're going to test for malignant hyperthermia. It's not associated with nemaline myopathy but is associated with a different myopathy that has a similar presentation.”
2. What does troponin do?
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Question #3:
In the KeyGene paper, the authors state that it would be useful if pollen from an apomict would
transmit apomixis-inducing genes to the female in the cross (assuming the pollen is viable). Assuming
there was just one gene conferring gametophytic obligate apomixis, and that the two parents are
inbreds, what would be the consequences of such a cross if:
a) The apomixis was a dominant trait? Indicate the genotypes and phenotypes (apomict or non-
apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic
and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female
first (left side) in the parental cross.
b) The apomixis was a recessive trait? Indicate the genotypes and phenotypes (apomict or non-
apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic
and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female
first (left side) in the…
Question #5:
Assume that two genes are identified that confer gametophytic facultative apomixis in soybean. The
genes show independent assortment. Recessive alleles at both loci are required for the facultative
apomixis. Facultative apomixis is triggered when the temperature at pollination is above 20 degrees C.
At temperatures below 20 degrees C, all reproduction is sexual, independent of genotype.
A facultative apomict male, capable of producing viable pollen, was crossed with a sexually
reproducing female. Assuming the parents are completely inbred, what are the predicted phenotypic
ratios (apomict: non-apomict) for the F1, F2, and DH (F1-derived) generations at each of the following
temperatures*:
a) 15°C?
b) 25°C?
*for full credit, show crosses and genotypes where appropriate. Remember to position the
female first (left side) in the cross.
Type your answer here:
a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
Chapter 9 Solutions
EBK HUMAN ANAT.+PHYSIOLOGY
Ch. 9 - Prob. 1RQCh. 9 - 2. A fascicle is a (a) muscle, (b) bundle of...Ch. 9 - 3. Thick and thin myofilaments have different...Ch. 9 - 4. The function of the T tubules in muscle...Ch. 9 - 5. The sites where the motor nerve impulse is...Ch. 9 - 6. Contraction elicited by a single brief stimulus...Ch. 9 - 7. A smooth, sustained contraction resulting from...Ch. 9 - 8. Characteristics of isometric contractions...Ch. 9 - 9. During muscle contraction, ATP is provided by...Ch. 9 - 10. The neurotransmitter released by somatic motor...
Ch. 9 - 11. The ions that enter the skeletal muscle cell...Ch. 9 - 12. Myoglobin has a special function in muscle...Ch. 9 - 13. Aerobic exercise results in all of the...Ch. 9 - 14. The smooth muscle type found in the walls of...Ch. 9 - 15. Name and describe the four special functional...Ch. 9 - 16. Distinguish between (a) direct and indirect...Ch. 9 - 17. (a) Describe the structure of a sarcomere and...Ch. 9 - 18. What is the importance of acetylcholinesterase...Ch. 9 - 19. Explain how a slight (but smooth) contraction...Ch. 9 - 20. Explain what is meant by the term...Ch. 9 - 21. Define and draw a motor unit.
Ch. 9 - 23. True or false: Most muscles contain a...Ch. 9 - 24. Describe some cause(s) of muscle fatigue and...Ch. 9 - 26. Smooth muscle has some unique properties, such...Ch. 9 - 2. When a suicide victim was found, the coroner...Ch. 9 - 3. Muscle-relaxing drugs are administered to a...Ch. 9 - Children with Muscular Disorders You're doing a...Ch. 9 - Children with Muscular Disorders
You're doing a...Ch. 9 - Children with Muscular Disorders
You're doing a...Ch. 9 - Children with Muscular Disorders
You're doing a...Ch. 9 - Children with Muscular Disorders You're doing a...Ch. 9 - Children with Muscular Disorders You're doing a...Ch. 9 - Children with Muscular Disorders
You're doing a...
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