HUMAN HEREDITY (LL)-W/MINDTAP ACCESS
HUMAN HEREDITY (LL)-W/MINDTAP ACCESS
11th Edition
ISBN: 9781305717022
Author: Cummings
Publisher: CENGAGE L
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Chapter 9, Problem 21QP
Summary Introduction

To explain: The reason which elaborates that none of the mutant protein product ends up in the cell’s plasma membrane during the cystic fibrosis.

Introduction: The cystic fibrosis is a disorder that mainly affects the lungs, but it also affects the liver, pancreas, and kidneys. The person having cystic fibrosis will have difficulty in breathing due to the development of mucus in the lungs.

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Noggin mutation: The mouse, one of the phenotypic consequences of Noggin mutationis mispatterning of the spinal cord, in the posterior region of the mouse embryo, suchthat in the hindlimb region the more ventral fates are lost, and the dorsal Pax3 domain isexpanded. (this experiment is not in the lectures).a. Hypothesis for why: What would be your hypothesis for why the ventral fatesare lost and dorsal fates expanded? Include in your answer the words notochord,BMP, SHH and either (or both of) surface ectoderm or lateral plate mesoderm

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HUMAN HEREDITY (LL)-W/MINDTAP ACCESS

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