BIOLOGY (OER)
2nd Edition
ISBN: 2810023110482
Author: OpenStax
Publisher: MBS
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Chapter 9, Problem 15RQ
How does NF-kB induce gene expression?
- A small, hydrophobic ligand binds to NF-kB, activating it.
- Phosphorylation of the inhibitor Ik-B dissociates the complex between it and NF- kB, and allows NF-kB to enter the nucleus and stimulate transcription.
- NF-kB is phosphorylated and is then free to enter the nucleus and bind DNA.
- NF-kB is a kinase that phosphorylates a transcription factor that binds DNA and promotes protein production.
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Chapter 9 Solutions
BIOLOGY (OER)
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