CAMPBELL BIOLOGY IN FOCUS-W/MASTR.BIO.
CAMPBELL BIOLOGY IN FOCUS-W/MASTR.BIO.
3rd Edition
ISBN: 9780134875040
Author: Urry
Publisher: PEARSON
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Chapter 9, Problem 11TYU

SYNTHESIZE YOUR KNOWLEDGE

Chapter 9, Problem 11TYU, SYNTHESIZE YOUR KNOWLEDGE Shown here are two He La cancer cells that are just completing

Shown here are two He La cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cells like these is misregulated. What genetic and other changes might have caused these cells to escape normal cell cycle regulation?

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Cancer cells typically lose cell cycle entry control. Explain how the following mutations, which are found in some cancer cells, lead to a bypass of these controls: (a) overexpression of cyclin D, (b) loss of Rb function, (c) loss of p16 function, (d) hyperactive E2F.
Despite being small animals, naked mole rats are almost entirely resistant to cancer. Watch the following brief video on one potential mechanism for the prevention of cancer in naked mole rats. https://youtu.be/bhNBeuhxkF0?si=38aelHLW1N6vN8-b Based on what you know about mitosis and cancer cells, why would a mechanism that prevents cell crowding reduce the likelihood of cancer developing?
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cell division of meiosis and mitosis; Author: Stated Clearly;https://www.youtube.com/watch?v=A-mFPZLLbHI;License: Standard youtube license