ANATOMY & PHYSIOLOGY ACCESS CARD
9th Edition
ISBN: 9781265896843
Author: SALADIN
Publisher: MCG
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Textbook Question
Chapter 8.5, Problem 8AYLO
Features of the femur, including the head, neck, fovea capitis, trochanters, intertrochanteric crest, gluteal tuberosity, condyles, intercondylar fossa, epicondyles, lines, and patellar and popliteal surfaces
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 8 Solutions
ANATOMY & PHYSIOLOGY ACCESS CARD
Ch. 8.1 - Name the major components of the axial skeleton....Ch. 8.1 - Explain why an adult doesnot have asmany bones as...Ch. 8.1 - Prob. 3BYGOCh. 8.1 - The difference between the axial and appendicular...Ch. 8.1 - The typical number of named bones in an adult; why...Ch. 8.1 - Prob. 3AYLOCh. 8.1 - Names of the various outgrowths, depressions,...Ch. 8.2 - Name the paranasal sinuses and state their...Ch. 8.2 - Explain the difference Between a cranial bone and...Ch. 8.2 - Prob. 6BYGO
Ch. 8.2 - Prob. 7BYGOCh. 8.2 - Prob. 8BYGOCh. 8.2 - Prob. 1AYLOCh. 8.2 - Prob. 2AYLOCh. 8.2 - The collective function of the skull foramina; the...Ch. 8.2 - Major features of the cranium; the difference...Ch. 8.2 - Names of the six different cranial bones; which...Ch. 8.2 - The location and extent of the frontal bone; the...Ch. 8.2 - Prob. 7AYLOCh. 8.2 - Prob. 8AYLOCh. 8.2 - The location and extent of the occipital boor, its...Ch. 8.2 - The location and extent of the sphenoid bone; its...Ch. 8.2 - Prob. 11AYLOCh. 8.2 - Prob. 12AYLOCh. 8.2 - Prob. 13AYLOCh. 8.2 - Prob. 14AYLOCh. 8.2 - Prob. 15AYLOCh. 8.2 - Prob. 16AYLOCh. 8.2 - Prob. 17AYLOCh. 8.2 - Prob. 18AYLOCh. 8.2 - Prob. 19AYLOCh. 8.2 - Prob. 20AYLOCh. 8.2 - Prob. 21AYLOCh. 8.2 - Prob. 22AYLOCh. 8.2 - Prob. 23AYLOCh. 8.2 - Names and locations of the fontanelles of the...Ch. 8.3 - Prob. 9BYGOCh. 8.3 - Prob. 10BYGOCh. 8.3 - Prob. 11BYGOCh. 8.3 - Prob. 12BYGOCh. 8.3 - Distinguish between true, false, aid floating...Ch. 8.3 - Prob. 14BYGOCh. 8.3 - Prob. 1AYLOCh. 8.3 - Prob. 2AYLOCh. 8.3 - Features of a typical vertebraCh. 8.3 - The five classes of vertebrae and the number of...Ch. 8.3 - Prob. 5AYLOCh. 8.3 - Prob. 6AYLOCh. 8.3 - Prob. 7AYLOCh. 8.3 - Prob. 8AYLOCh. 8.3 - Prob. 9AYLOCh. 8.3 - Prob. 10AYLOCh. 8.3 - Prob. 11AYLOCh. 8.3 - Prob. 12AYLOCh. 8.3 - Prob. 13AYLOCh. 8.3 - Prob. 14AYLOCh. 8.3 - Which ribs differ from that typical anatomy, and...Ch. 8.3 - Prob. 16AYLOCh. 8.4 - Prob. 15BYGOCh. 8.4 - Prob. 16BYGOCh. 8.4 - What three bones meet at the elbow? Identify the...Ch. 8.4 - Prob. 18BYGOCh. 8.4 - Prob. 19BYGOCh. 8.4 - Names and locations of the 4 bones of the pectoral...Ch. 8.4 - Names of the joints at which the humerus...Ch. 8.4 - Features of the clavicle, including the sternal...Ch. 8.4 - Prob. 4AYLOCh. 8.4 - Prob. 5AYLOCh. 8.4 - Prob. 6AYLOCh. 8.4 - Prob. 7AYLOCh. 8.4 - Prob. 8AYLOCh. 8.4 - Prob. 9AYLOCh. 8.4 - Prob. 10AYLOCh. 8.5 - Prob. 20BYGOCh. 8.5 - Prob. 21BYGOCh. 8.5 - Prob. 22BYGOCh. 8.5 - Prob. 23BYGOCh. 8.5 - Prob. 24BYGOCh. 8.5 - Prob. 25BYGOCh. 8.5 - Prob. 1AYLOCh. 8.5 - Prob. 2AYLOCh. 8.5 - Prob. 3AYLOCh. 8.5 - Three childhood bones that fuse to form each adult...Ch. 8.5 - Prob. 5AYLOCh. 8.5 - Prob. 6AYLOCh. 8.5 - Names of the four regions of the lower limb and...Ch. 8.5 - Features of the femur, including the head, neck,...Ch. 8.5 - Prob. 9AYLOCh. 8.5 - Features of the tibia, including the lateral and...Ch. 8.5 - Prob. 11AYLOCh. 8.5 - Prob. 12AYLOCh. 8.5 - Prob. 13AYLOCh. 8.5 - Why the elbows and knees flex in opposite...Ch. 8.5 - Names and locations of the three foot archesCh. 8 - Prob. 1TYRCh. 8 - Prob. 2TYRCh. 8 - Prob. 3TYRCh. 8 - All of the following are groups of vertebrae...Ch. 8 - Prob. 5TYRCh. 8 - The tubercle of a rib articulates with a. the...Ch. 8 - The disc-shaped head of the radius articulates...Ch. 8 - Prob. 8TYRCh. 8 - Prob. 9TYRCh. 8 - Prob. 10TYRCh. 8 - Prob. 11TYRCh. 8 - The external auditory canal is a passage in the...Ch. 8 - Prob. 13TYRCh. 8 - The __________ bone has greater and lesser wings...Ch. 8 - Prob. 15TYRCh. 8 - Prob. 16TYRCh. 8 - Prob. 17TYRCh. 8 - Prob. 18TYRCh. 8 - Prob. 19TYRCh. 8 - Prob. 20TYRCh. 8 - Prob. 1BYMVCh. 8 - Prob. 2BYMVCh. 8 - Prob. 3BYMVCh. 8 - Prob. 4BYMVCh. 8 - Prob. 5BYMVCh. 8 - Prob. 6BYMVCh. 8 - Prob. 7BYMVCh. 8 - Prob. 8BYMVCh. 8 - Prob. 9BYMVCh. 8 - Prob. 10BYMVCh. 8 - Prob. 1WWTSCh. 8 - Prob. 2WWTSCh. 8 - Prob. 3WWTSCh. 8 - Prob. 4WWTSCh. 8 - Prob. 5WWTSCh. 8 - Prob. 6WWTSCh. 8 - Prob. 7WWTSCh. 8 - The most frequently broken bone is the humerus.Ch. 8 - Prob. 9WWTSCh. 8 - Sesamoid bones are found along the sutures between...Ch. 8 - Prob. 1TYCCh. 8 - Prob. 2TYCCh. 8 - Between any two of the unfused vertebrae (cervical...Ch. 8 - In adolescents, trauma sometimes separates the...Ch. 8 - Prob. 5TYC
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