Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 8.1, Problem 1AYP
Describe the relationship among
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 8 Solutions
Microbiology: A Systems Approach
Ch. 8.1 - Describe the relationship among metabolism,...Ch. 8.1 - Fully discuss the structure and function of...Ch. 8.1 - Differentiate between an apoenzyme and a...Ch. 8.1 - Differentiate between an endoenzyme and an...Ch. 8.1 - Diagram the four major patterns of metabolism.Ch. 8.1 - Describe how enzymes are controlled.Ch. 8.2 - Name the chemical in which energy is stored in...Ch. 8.2 - Create a general diagram of a redox reaction.Ch. 8.2 - Identify electron carriers used by cells.Ch. 8.3 - List three basic catabolic pathways and the...
Ch. 8.3 - Construct a paragraph summarizing glycolysis.Ch. 8.3 - Describe the Krebs cycle and compare the process...Ch. 8.3 - Discuss the significance of the electron transport...Ch. 8.3 - State two ways in which anaerobic respiration...Ch. 8.3 - Summarize the steps of microbial fermentation and...Ch. 8.3 - Prob. 16AYPCh. 8.4 - Prob. 17AYPCh. 8.4 - Define amphibolism.Ch. 8.5 - Summarize the overall process of photosynthesis in...Ch. 8.5 - Discuss the relationship between light-dependent...Ch. 8.5 - Explain the role of the Calvin cycle in the...Ch. 8 - Prob. 1MCQCh. 8 - An enzyme a. becomes part of the final products....Ch. 8 - An apoenzyme is where the ____ is located. a....Ch. 8 - Many coenzymes are a. metals. b. vitamins. c....Ch. 8 - Prob. 5MCQCh. 8 - Energy is carried from catabolic to anabolic...Ch. 8 - A product or products of glycolysis is/are a. ATP....Ch. 8 - Prob. 8MCQCh. 8 - Complete oxidation of glucose in aerobic...Ch. 8 - ATP synthase complexes can generate ______ ATP(s)...Ch. 8 - True-False Questions. If the statement is true,...Ch. 8 - An enzyme lowers the activation energy required...Ch. 8 - One cycle of fermentation yields more energy than...Ch. 8 - Energy in biological systems is primarily...Ch. 8 - Exoenzymes are produced outside the cell.Ch. 8 - Prob. 1CTQCh. 8 - Prob. 2CTQCh. 8 - Compare and contrast the processes of...Ch. 8 - Draw a bacterial cell and a eukaryotic cell side...Ch. 8 - Provide evidence in support of or refuting the...Ch. 8 - From chapter 4, figure 4.16. On the enlarged...Ch. 8 - Using the words that follow, please create a...
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