Essential Cell Biology
Essential Cell Biology
4th Edition
ISBN: 9780815344544
Author: Keith Roberts, Karen Hopkin, Alexander D Johnson, Martin Raff, Dennis Bray, Bruce Alberts, Julian Lewis, Peter Walter
Publisher: TAYLOR
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Chapter 8, Problem 6Q
Summary Introduction

To explain: The expected results of the given experiment.

Concept introduction:

Transcription process marks the beginning of gene expression. Transcription factors are the proteins that function in transcribing DNA to mRNA. Enhancers are distal control elements located away from the transcribing gene. The control elements of enhancers are short DNA nucleotide sequences. They regulate the expression of specific target genes by binding to the specific transcription factors. These may be activators (activate transcription) or repressors (repress transcription).

Given:

The experiment is designed in Professor Q’s laboratory to determine how far an enhancer be moved from the promoter region of the straight spine gene and still initiate transcription. In order to determine this, the numbers of nucleotide pairs are varied between promoter and enhancer sites. The graph shows the data after measuring the production of straight spine mRNA.

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