Applications of Microsoft Excel in Analytical Chemistry
Applications of Microsoft Excel in Analytical Chemistry
2nd Edition
ISBN: 9781285629575
Author: Holler, F. James, Crouch, Stanley R.
Publisher: Cengage Learning
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2) There are many forms of cancer, all of which involve abnormal cell growth. The growth and production of cells, called cell proliferation, is known to involve an enzyme called protein farnesyltransferase (PFTase). It is thought that inhibitors pf PFTase may be useful as anticancer drugs. The following molecule showed moderate activity as a potential PFTase inhibitor. Draw all stereoisomers of this compound. HO OH
Considering rotation around the bond highlighted in red, draw the Newman projection for the most stable and least stable conformations when viewed down the red bond in the direction of the arrow. Part 1 of 2 H₁₂C H H Draw the Newman projection for the most stable conformation. Select a template to begin. Part 2 of 2 Draw the Newman projection for the least stable conformation. G 心
personality of each of them in terms of nucleophile vs. electrophile (some can be considered acids/bases but we are not looking at that here). Note you may have to use your growing intuition to figure out the personality of one of the molecules below but I believe in you! Rationalize it out based on what we have called strong versus weak electrophiles in past mechanisms. Consider using the memes below to help guide your understanding! A OH O B CH3 C Molecule A: [Select] Molecule B: [Select] Molecule C: [Select] Molecule D: [Select] > H D OH
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