MAST F/ CHEM: THE CENTRAL SCI CODE ALON
14th Edition
ISBN: 9781323654378
Author: Brown
Publisher: PEARSON
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Chapter 8, Problem 47E
(a)
Interpretation Introduction
To determine: Lewis structure for
(b)
Interpretation Introduction
To determine: Lewis structure for
(c)
Interpretation Introduction
To determine: Lewis structure for
(d)
Interpretation Introduction
To determine: Lewis structure for
(e)
Interpretation Introduction
To determine: Lewis structure for
(f)
Interpretation Introduction
To determine: Lewis structure for
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
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Chapter 8 Solutions
MAST F/ CHEM: THE CENTRAL SCI CODE ALON
Ch. 8.2 - Which of the these elements is most likely to from...Ch. 8.2 - Prob. 8.1.2PECh. 8.2 - Which of the following bond is the most polar? H-F...Ch. 8.2 - Prob. 8.2.2PECh. 8.3 - Prob. 8.3.1PECh. 8.3 - Prob. 8.3.2PECh. 8.4 - Which of the following bonds is the most polar? a....Ch. 8.4 - Which of the following bonds is most polar: S-Cl,...Ch. 8.4 - Prob. 8.5.1PECh. 8.4 - The dipole moment of chlorine monofluoride,...
Ch. 8.5 - Which of the these molecules has a Lewis structure...Ch. 8.5 -
How many valence electrons should appear in the...Ch. 8.5 - Compare the lewis symbol for neon the structure...Ch. 8.5 - Prob. 8.7.2PECh. 8.5 - Prob. 8.8.1PECh. 8.5 - Prob. 8.8.2PECh. 8.5 - Prob. 8.9.1PECh. 8.5 - Prob. 8.9.2PECh. 8.6 - Which of the statements about resonance is true?...Ch. 8.6 - Prob. 8.10.2PECh. 8.7 - Prob. 8.11.1PECh. 8.7 - Prob. 8.11.2PECh. 8 - Prob. 1DECh. 8 - Prob. 1ECh. 8 - Prob. 2ECh. 8 - A portion of a two-dimensional "slab" of NaCl(s)...Ch. 8 - Prob. 4ECh. 8 - Prob. 5ECh. 8 - Incomplete Lewis structures for the nitrous acid...Ch. 8 - Prob. 7ECh. 8 - Prob. 8ECh. 8 - Prob. 9ECh. 8 - True or false: The hydrogen atom is most stable...Ch. 8 - Consider the element silicon, Si. Write its...Ch. 8 - Write the electron configuration for the element...Ch. 8 - Prob. 13ECh. 8 - What is the Lewis symbol for each of the following...Ch. 8 - Using Lewis symbols, diagram the reaction between...Ch. 8 - Use Lewis symbols to represent the reaction that...Ch. 8 - Predict the chemical formula of the ionic compound...Ch. 8 - Prob. 18ECh. 8 - Prob. 19ECh. 8 - Prob. 20ECh. 8 - Is lattice energy usually endothermic or...Ch. 8 - NaCI and KF have the same crystal structure. The...Ch. 8 - Prob. 23ECh. 8 - Prob. 24ECh. 8 - Consider the ionic compounds KF, NaCl, NaBr, and...Ch. 8 - Which of the following trends in lattice energy is...Ch. 8 - Energy is required to remove two electrons from Ca...Ch. 8 - Prob. 28ECh. 8 - Use data from Appendix C, Figure 7.10, and Figure...Ch. 8 - Prob. 30ECh. 8 - Prob. 31ECh. 8 - Prob. 32ECh. 8 - Using Lewis symbols and Lewis structures, diagram...Ch. 8 - Use Lewis symbols and Lewis structures to diagram...Ch. 8 - Prob. 35ECh. 8 - Prob. 36ECh. 8 - Prob. 37ECh. 8 - What is the trend in electronegativity going from...Ch. 8 - Prob. 39ECh. 8 - By referring only to the periodic table, select...Ch. 8 - which of the following bonds are polar? B-F,...Ch. 8 - Arrange the bonds in each of the following sets in...Ch. 8 - Prob. 43ECh. 8 - Prob. 44ECh. 8 - In the following pairs of binary compounds,...Ch. 8 - Prob. 46ECh. 8 - Prob. 47ECh. 8 - Write Lewis structures for the following: H2CO...Ch. 8 - Prob. 49ECh. 8 - Draw the dominant Lewis structure for the...Ch. 8 - Write Lewis structures that obey the octet rule...Ch. 8 - Prob. 52ECh. 8 - Prob. 53ECh. 8 - Prob. 54ECh. 8 - Prob. 55ECh. 8 - Prob. 56ECh. 8 - Prob. 57ECh. 8 - Prob. 58ECh. 8 - Prob. 59ECh. 8 - Prob. 60ECh. 8 - Prob. 61ECh. 8 - 8.62 For Group 3A-7A elements in the third row of...Ch. 8 - Draw the Lewis structures for each of the...Ch. 8 - Prob. 64ECh. 8 - In the vapor phase, BeCl2exists as a discrete...Ch. 8 -
8.66
Describe the molecule xenon trioxide, XeO3,...Ch. 8 -
8.67 There are many Lewis structures you could...Ch. 8 - Prob. 68ECh. 8 - Using Table 8.3, estimate H for each of the...Ch. 8 - Using Table 8.3, estimate H for the following...Ch. 8 - State whether each of these statements is true or...Ch. 8 - Prob. 72ECh. 8 - Prob. 73ECh. 8 - Prob. 74ECh. 8 - Prob. 75ECh. 8 - Prob. 76ECh. 8 - A new compound is made that has a C-C bond length...Ch. 8 - A new compound is made that has an N-N bond length...Ch. 8 - Prob. 79AECh. 8 - Prob. 80AECh. 8 - An ionic substance of formula MX has a lattice...Ch. 8 - Prob. 82AECh. 8 - Prob. 83AECh. 8 - Prob. 84AECh. 8 - Consider the collection of nonmetallic elements 0,...Ch. 8 - The substance chlorine monoxide, CIO(g), is...Ch. 8 -
[8.87]
a. using the electronegativities of Br...Ch. 8 - Prob. 88AECh. 8 - Although I3- is a known ion, F3- is not. a. Draw...Ch. 8 - Calculate the formal charge on the indicated atom...Ch. 8 - The hypochlorite ion, CIO- , is the active...Ch. 8 - Prob. 92AECh. 8 - a. Triazine, C3 H3N3, is like benzene except that...Ch. 8 - Prob. 94IECh. 8 - Prob. 95IECh. 8 - Prob. 96IECh. 8 - Prob. 97IECh. 8 - Prob. 98IECh. 8 - Prob. 99IECh. 8 - Prob. 100IECh. 8 - Prob. 101IECh. 8 - Prob. 102IECh. 8 -
8.103 The compound chloral hydrate, known in...Ch. 8 - Barium azide is 62.04% Ba and 37.96% N. Each azide...Ch. 8 - Acetylene (C2H2) and nitrogen (N2) both contain a...Ch. 8 - Prob. 106IECh. 8 - Prob. 107IECh. 8 -
8.108 Formic acid has the chemical formula...Ch. 8 - Prob. 109IECh. 8 - Prob. 110IE
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